Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 10/20 | 0.67 |
| ▸ | TP53 | P04637 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13105877 | 0.85 | ALOX5 (0.67) | ALOX5MAPTPOLBAPEX1RECQL | |
| SCHEMBL14420740 | 0.85 | ALOX5 (0.67) | ALOX5MAPTPOLBAPEX1RECQL | |
| SCHEMBL11829466 | 0.81 | ALOX5 (0.73) | ALOX5MAPTPOLBAPEX1RECQL | |
| SCHEMBL1286369 | 0.81 | POLB (0.79) | ALOX5MAPTPOLBAPEX1RECQL | |
| Benzene SCHEMBL28322799 | 0.81 | POLB (0.79) | ALOX5MAPTPOLBAPEX1RECQL | |
| SCHEMBL13629728 | 0.79 | MAPT (1.00) | ALOX5MAPTPOLBAPEX1RECQL | |
| SCHEMBL13461102 | 0.77 | POLB (0.83) | ALOX5MAPTPOLBAPEX1RECQL | |
| SCHEMBL2261407 | 0.76 | POLB (0.77) | ALOX5MAPTPOLBAPEX1RECQL | |
| SCHEMBL5401249 | 0.76 | POLB (0.77) | ALOX5MAPTPOLBAPEX1RECQL | |
| SCHEMBL9220907 | 0.76 | ALDH1A1 (0.70) | ALOX5MAPTTP53POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170020858-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES INC (US) | 2017-01-26 | — | — | US | disclosed |
| US-20170020858-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES INC (US) | 2017-01-26 | — | — | US | disclosed |
| US-20150299225-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2015-10-22 | — | — | US | disclosed |
| US-20150299225-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2015-10-22 | — | — | US | disclosed |
| US-8916550-B2 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2014-12-23 | — | — | US | disclosed |
| US-8916550-B2 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2014-12-23 | — | — | US | disclosed |
| EP-2392328-A1 | Compounds for modulating TRPV3 Function | Hydra Biosciences, Inc. (US) | 2011-12-07 | — | — | EP | disclosed |
| US-20100273777-A1 | Compounds for Modulating TRPV3 Function | HYDRA BIOSCIENCES, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100273777-A1 | Compounds for Modulating TRPV3 Function | HYDRA BIOSCIENCES, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| US-7803790-B2 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-7803790-B2 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2010-09-28 | — | — | US | disclosed |
| WO-2008060626-A9 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES INC (US) | 2008-07-31 | — | — | WO | disclosed |
| WO-2008060626-A2 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2008-05-22 | — | — | WO | disclosed |
| US-20070213321-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213321-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170020858-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | TRPV3, TRPV1, TRPV4 | ALOX5 802/4885MAPT 1751/4885TP53 4750/4885 |
| US-20150299225-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | TRPV3, TRPV1, TRPV4 | ALOX5 802/4885MAPT 1751/4885TP53 4750/4885 |
| US-20100273777-A1 | Compounds for Modulating TRPV3 Function | TRPV3, TRPV1, TRPV4 | ALOX5 802/4885MAPT 1751/4885TP53 4750/4885 |
| US-20070213321-A1 | Compounds for modulating TRPV3 function | TRPV3, TRPV1, TRPV4 | ALOX5 802/4885MAPT 1751/4885TP53 4750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.