Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12038288 | 0.93 | KDM4E (0.49) | KMT2AKDM4EGLAGAAMEN1 | |
| SCHEMBL12038303 | 0.82 | MAOB (0.40) | KMT2AKDM4EGLAGAAMEN1 | |
| SCHEMBL12038321 | 0.80 | GAPDH (0.39) | KMT2AKDM4EGLAGAAMEN1 | |
| SCHEMBL13494166 | 0.78 | GPR35 (0.41) | KMT2AKDM4EMEN1ALDH1A1HSD17B10 | |
| SCHEMBL17942948 | 0.75 | RAB9A (0.50) | KMT2AKDM4EGLAGAAMEN1 | |
| SCHEMBL12038319 | 0.72 | KDM4E (0.54) | KMT2AKDM4EGLAGAAMEN1 | |
| SCHEMBL12038323 | 0.71 | MAOB (0.38) | KMT2AKDM4EGLAGAAMEN1 | |
| SCHEMBL12038427 | 0.71 | KDM4E (0.39) | KMT2AKDM4EGLAGAAMEN1 | |
| SCHEMBL17942933 | 0.70 | KDM4E (0.62) | KMT2AKDM4EGLAGAAMEN1 | |
| SCHEMBL12038347 | 0.69 | GLA (0.38) | KMT2AKDM4EGLAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318953-B2 | Reactive coumarin derivatives and their use in cellular analyses | AAT BIOQUEST, INC. (US) | 2012-11-27 | — | — | US | disclosed |