SCHEMBL120478

SCHEMBL120478

O=C(O)[C@@H]1CCN1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.49
FABP7 O15540 2/20 0.49
ALDH1A1 P00352 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KMT2A Q03164 2/20 0.44
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
EPHX2 P34913 1/20 0.41
RAB9A P51151 1/20 0.41
OPRD1 P41143 1/20 0.40
PREP P48147 1/20 0.38
MDM4 O15151 1/20 0.38
TP53 P04637 1/20 0.38
CASP3 P42574 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29447569 1.00 FABP5 (0.49) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL119436 1.00 FABP5 (0.49) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL30063787 1.00 FABP5 (0.49) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL29540385 1.00 FABP5 (0.49) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL1847817 1.00 FABP5 (0.49) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL29447611 1.00 FABP5 (0.49) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL29549607 0.92 ALDH1A1 (0.58) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL29503800 0.92 ALDH1A1 (0.58) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL29503770 0.92 ALDH1A1 (0.58) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL119560 0.92 ALDH1A1 (0.58) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 EP disclosed
US-12503491-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 US disclosed
EP-3727462-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLERD LTD (GB) 2025-11-05 EP disclosed
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-09 US disclosed
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-02 US disclosed
US-20250257094-A1 METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-14 US disclosed
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-29 US disclosed
US-20250230193-A1 CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-07-17 US disclosed
EP-3727461-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLETX LTD (GB) 2025-07-09 EP disclosed
EP-4582436-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BicycleTX Limited (GB) 2025-07-09 EP disclosed
US-20070042401-A1 Methods for synthesis of encoded libraries PRAECIS PHARMACEUTICALS, INC. (US) 2007-02-22 US disclosed
US-6528503-B2 Anticoagulants MERCK & CO., INC. 2003-03-04 US disclosed
US-20030013700-A1 Thrombin inhibitors MERCK SHARP & DOHME CORP. 2003-01-16 US disclosed
EP-0502926-B1 ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES RHONE POULENC RORER INT (US) 1996-03-13 EP disclosed
US-5328900-A Anti-thrombotic peptide and pseudopeptide derivatives RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1994-07-12 US disclosed
EP-0502926-A1 ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. RHONE POULENC RORER INT (US) 1992-09-16 EP disclosed
EP-0502926-A4 ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. RHONE POULENC RORER INTERNAT H (US) 1992-07-13 EP disclosed
US-5064814-A Anti-thrombotic peptide and pseudopeptide derivatives RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1991-11-12 US disclosed
US-5053392-A Anticoagulants RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1991-10-01 US disclosed
WO-1991007976-A1 ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1991-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503491-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 FABP5 1093/4885FABP7 2453/4885ALDH1A1 2138/4885
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS KRAS, HRAS, NRAS FABP5 4631/4885FABP7 4721/4885ALDH1A1 4331/4885
US-20030013700-A1 Thrombin inhibitors TFPI, PLAT, TFPI2 FABP5 2498/4885FABP7 4324/4885ALDH1A1 2961/4885
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid DNPEP, VIP, NPEPPS FABP5 3048/4885FABP7 2102/4885ALDH1A1 4328/4885
US-20250230193-A1 CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS KRAS, HRAS, NRAS FABP5 4631/4885FABP7 4721/4885ALDH1A1 4331/4885
US-20250257094-A1 METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES NGLY1, NPPA, VIP FABP5 3043/4885FABP7 2774/4885ALDH1A1 4672/4885
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action KRAS, NRAS, HRAS FABP5 4094/4885FABP7 4602/4885ALDH1A1 4838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.