SCHEMBL29540385

SCHEMBL29540385

O=C(O)[C@@H]1CCN1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.49
FABP7 O15540 2/20 0.49
ALDH1A1 P00352 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KMT2A Q03164 2/20 0.44
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
EPHX2 P34913 1/20 0.41
RAB9A P51151 1/20 0.41
OPRD1 P41143 1/20 0.40
PREP P48147 1/20 0.38
MDM4 O15151 1/20 0.38
TP53 P04637 1/20 0.38
CASP3 P42574 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29447569 1.00 FABP5 (0.49) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL119436 1.00 FABP5 (0.49) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL30063787 1.00 FABP5 (0.49) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL120478 1.00 FABP5 (0.49) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL1847817 1.00 FABP5 (0.49) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL29447611 1.00 FABP5 (0.49) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL29549607 0.92 ALDH1A1 (0.58) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL29503800 0.92 ALDH1A1 (0.58) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL29503770 0.92 ALDH1A1 (0.58) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A
SCHEMBL119560 0.92 ALDH1A1 (0.58) FABP5FABP7ALDH1A1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663653-A1 METHOD FOR PRODUCING EUTECTIC OF CYCLIC PEPTIDE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-12-17 EP disclosed
US-20250353875-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-11-20 US disclosed
EP-3650464-B1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND SHANGPHARMA INNOVATION INC (US) 2025-11-05 EP disclosed
US-20250302912-A1 COMPOSITION INCLUDING PEPTIDE COMPOUND AND SURFACTANT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-10-02 US disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-09 US disclosed
US-20250276995-A1 PRODUCTION METHOD FOR PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-04 US disclosed
EP-4609875-A2 COMPOSITION CONTAINING PEPTIDE COMPOUND AND SURFACTANT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-03 EP disclosed
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-02 US disclosed
EP-4603105-A1 PHARMACEUTICAL COMPOSITION CONTAINING CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT AGAINST HRAS AND NRAS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-20 EP disclosed
WO-2022234852-A1 PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND 中外製薬株式会社 2022-11-10 WO disclosed
EP-4086272-A1 METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-11-09 EP disclosed
EP-4056580-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-09-14 EP disclosed
US-11427615-B2 Peptide compound and application thereof, and composition containing peptide compound XDCEXPLORER (SHANGHAI) CO., LTD. (CN) 2022-08-30 US disclosed
EP-4046982-A1 METHOD FOR QUANTIFYING AMINO GROUP-CONTAINING COMPOUND PROTECTED BY PROTECTING GROUP HAVING FMOC SKELETON CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-08-24 EP disclosed
EP-4043478-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITING ACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-08-17 EP disclosed
CN-109134610-B Peptide compound, application thereof and composition containing peptide compound 尚华医药科技(江西)有限公司 2022-07-08 CN disclosed
CN-114630835-A Process for the preparation of peptide compounds comprising sterically bulky amino acids 中外制药株式会社 2022-06-14 CN disclosed
CN-114585916-A Method for quantifying compound having amino group protected with protecting group having Fmoc skeleton 中外制药株式会社 2022-06-03 CN disclosed
EP-3974563-A1 CYCLIC PEPTIDES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11427615-B2 Peptide compound and application thereof, and composition containing peptide compound KISS1R, VIP, NPY1R FABP5 2014/4885FABP7 692/4885ALDH1A1 4326/4885
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS KRAS, HRAS, NRAS FABP5 4631/4885FABP7 4721/4885ALDH1A1 4331/4885
US-20250276995-A1 PRODUCTION METHOD FOR PEPTIDE COMPOUND VIP, IAPP, QPCT FABP5 1731/4885FABP7 1335/4885ALDH1A1 4644/4885
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid DNPEP, VIP, NPEPPS FABP5 3048/4885FABP7 2102/4885ALDH1A1 4328/4885
US-20250353875-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION VIP, NPPA, DNPEP FABP5 3537/4885FABP7 3487/4885ALDH1A1 4554/4885
US-20250302912-A1 COMPOSITION INCLUDING PEPTIDE COMPOUND AND SURFACTANT PCTP, CETP, PLTP FABP5 265/4885FABP7 645/4885ALDH1A1 4623/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R FABP5 2565/4885FABP7 3166/4885ALDH1A1 4857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.