Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499517 | 0.94 | KDM4E (0.34) | ELANEKDM4EL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL951097 | 0.87 | PTGS2 (0.35) | ELANEMEN1KMT2APTGS2PTGS1 | |
| SCHEMBL25235198 | 0.86 | MAPT (0.35) | ELANEKDM4EL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL950884 | 0.86 | KDM4E (0.34) | ELANEKDM4EL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL30466609 | 0.86 | MAPT (0.35) | ELANEKDM4EL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL950989 | 0.86 | KDM4E (0.34) | ELANEKDM4EL3MBTL1MEN1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL25275402 | 0.86 | MAPT (0.35) | ELANEKDM4EL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL30466601 | 0.86 | MAPT (0.35) | ELANEKDM4EL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL950940 | 0.85 | ELANE (0.45) | ELANEKDM4EL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL950826 | 0.85 | KDM4E (0.36) | KDM4EL3MBTL1MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084474-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100168066-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168066-A1 | NOVEL INSECTICIDES | DDT, ACHE, CYP4F11 | ELANE 4156/4885KDM4E 3059/4885L3MBTL1 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.