SCHEMBL950940

SCHEMBL950940

Cc1cccc2c(=O)oc(-c3cc(C(F)(F)F)nn3-c3ncccc3Cl)nc12

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 7/20 0.45
▸ DHODH Q02127 2/20 0.36
▸ CARM1 Q86X55 1/20 0.36
▸ KDM4E B2RXH2 2/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ RXRA P19793 3/20 0.35
▸ NR1H2 P55055 3/20 0.35
▸ NR1H3 Q13133 3/20 0.35
▸ MAPT P10636 2/20 0.34
▸ MEN1 O00255 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ OPRL1 P41146 1/20 0.33
▸ PTGS1 P23219 1/20 0.33
▸ PTGS2 P35354 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL950425 0.93 KDM4E (0.37) ELANEDHODHCARM1KDM4EL3MBTL1
SCHEMBL30466609 0.90 MAPT (0.35) ELANEDHODHCARM1KDM4EL3MBTL1
SCHEMBL499517 0.90 KDM4E (0.34) ELANEDHODHCARM1KDM4EL3MBTL1
SCHEMBL25235198 0.90 MAPT (0.35) ELANEDHODHCARM1KDM4EL3MBTL1
SCHEMBL950884 0.90 KDM4E (0.34) ELANEDHODHCARM1KDM4EL3MBTL1
SCHEMBL30466601 0.89 MAPT (0.35) ELANEDHODHCARM1KDM4EL3MBTL1
SCHEMBL950989 0.89 KDM4E (0.34) ELANEDHODHCARM1KDM4EL3MBTL1
Ammonia Solution, Strong SCHEMBL25275402 0.89 MAPT (0.35) ELANEDHODHCARM1KDM4EL3MBTL1
SCHEMBL951078 0.89 DHODH (0.34) ELANEDHODHCARM1KDM4EL3MBTL1
SCHEMBL12911905 0.87 KDM4E (0.35) ELANEDHODHCARM1KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2256112-B1 Anthranilamides, process for the production thereof and pest controllers containing the same ISHIHARA SANGYO KAISHA (JP) 2016-01-13 — — EP disclosed
US-9173400-B2 Anthranilamide arthropodicide treatment E I DU PONT DE NEMOURS AND COMPANY (US) 2015-11-03 — — US disclosed
US-9113630-B2 Method of controlling particular insect pests by applying anthranilamide compounds E I DU PONT DE NEMOURS AND COMPANY (US) 2015-08-25 — — US disclosed
US-20140140973-A1 METHOD OF CONTROLLING PARTICULAR INSECT PESTS BY APPLYNG ANTHRANILAMIDE COMPOUNDS E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-22 — — US disclosed
US-20140141972-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E I DU PONT NEMOURS AND COMPANY (US) 2014-05-22 — — US disclosed
US-8697734-B2 Method for controlling particular insect pests by applying anthranilamide compounds E I DU PONT DE NEMOURS AND COMPANY (US) 2014-04-15 — — US disclosed
US-8637552-B2 Anthranilamide arthropodicide treatment E I DU PONT DE NEMOURS AND COMPANY (US) 2014-01-28 — — US disclosed
EP-1416796-B1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS DU PONT (US) 2013-03-27 — — EP disclosed
US-20130031677-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-31 — — US disclosed
US-20130028879-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-31 — — US disclosed
US-7179824-B2 E.g., N-(3-chloro-2-pyridinyl)-N-[2-methyl-6-[[(1-methylethyl)amino]carbonyl]phenyl]-5-(trifluoromethyl)-1H-pyrazole-3-carboxamide; control of foliar- and soil-inhabiting arthropods and protection of agronomic and/or nonagronomic crops; veterinary medicine;environmentally friendly E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-02-20 — — US disclosed
EP-1717237-A1 ANTHRANILAMIDES, PROCESS FOR THE PRODUCTION THEREOF, AND PEST CONTROLLERS CONTAINING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-11-02 — — EP disclosed
EP-1438305-B1 ARTHROPODICIDAL ANTHRANILAMIDES DU PONT (US) 2006-08-23 — — EP disclosed
US-20050075372-A1 Method for controlling particular insect pest by applying anthranilamide compounds E. I. DU PONT DE NEMOURS AND COMPANY 2005-04-07 — — US disclosed
US-20040209923-A1 Anthranilamide arthropodicide treatment FMC CORPORATION 2004-10-21 — — US disclosed
US-20040186141-A1 Arthropodicidal anthranilamides E. I. DU PONT DE NEMOURS AND COMPANY 2004-09-23 — — US disclosed
EP-1438305-A1 ARTHROPODICIDAL ANTHRANILAMIDES E. I. du Pont de Nemours and Company (US) 2004-07-21 — — EP disclosed
EP-1427285-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E. I. du Pont de Nemours and Company (US) 2004-06-16 — — EP disclosed
WO-2003027099-A1 ARTHROPODICIDAL ANTHRANILAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-04-03 — — WO disclosed
WO-2003024222-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-03-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140140973-A1 METHOD OF CONTROLLING PARTICULAR INSECT PESTS BY APPLYNG ANTHRANILAMIDE COMPOUNDS ANTXR2, NIT2, TDO2 ELANE 2683/4885DHODH 1263/4885CARM1 429/4885
US-20130031677-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT ANTXR2, ARF5, NPR1 ELANE 3134/4885DHODH 1348/4885CARM1 780/4885
US-20040209923-A1 Anthranilamide arthropodicide treatment ANTXR2, ARF5, NPM1 ELANE 2332/4885DHODH 1442/4885CARM1 1006/4885
US-20040186141-A1 Arthropodicidal anthranilamides ANTXR2, NIT2, NQO2 ELANE 579/4885DHODH 582/4885CARM1 3031/4885
US-20130028879-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS ANTXR2, CYP4X1, PRDX1 ELANE 3002/4885DHODH 1151/4885CARM1 1892/4885
US-20050075372-A1 Method for controlling particular insect pest by applying anthranilamide compounds ANTXR2, HRH4, HDAC10 ELANE 2869/4885DHODH 1353/4885CARM1 417/4885
US-20140141972-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT ANTXR2, ARF5, NPR1 ELANE 3134/4885DHODH 1348/4885CARM1 780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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