SCHEMBL1206535

SCHEMBL1206535

S=C(SSSSC(=S)N(Cc1ccccc1)Cc1ccccc1)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.85
ALDH1A1 P00352 5/20 0.68
ALDH2 P05091 2/20 0.47
GAA P10253 1/20 0.46
FAAH O00519 1/20 0.43
LMNA P02545 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
RECQL P46063 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TSHR P16473 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bis(Dibenzylaminethiocarbonyl)Disulfide SCHEMBL80045 0.92 MGLL (1.00) MGLLALDH1A1ALDH2GAAFAAH
SCHEMBL26539452 0.85 MGLL (0.79) MGLLALDH1A1ALDH2GAAFAAH
SCHEMBL9242574 0.85 MGLL (0.79) MGLLALDH1A1ALDH2GAAFAAH
SCHEMBL13951496 0.85 MGLL (0.79) MGLLALDH1A1ALDH2GAAFAAH
SCHEMBL809716 0.83 MGLL (0.77) MGLLALDH1A1GAAFAAHLMNA
SCHEMBL6534613 0.83 MGLL (0.82) MGLLALDH1A1ALDH2GAAFAAH
SCHEMBL23927810 0.82 MGLL (0.73) MGLLALDH1A1ALDH2GAAFAAH
SCHEMBL22749343 0.82 MGLL (0.73) MGLLALDH1A1ALDH2GAAFAAH
SCHEMBL29677031 0.82 MGLL (0.73) MGLLALDH1A1ALDH2GAAFAAH
SCHEMBL23603515 0.82 MGLL (0.73) MGLLALDH1A1ALDH2GAAFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0284649-A1 Vulcanisation accelerator Firma Carl Freudenberg (DE) 1988-10-05 EP claimed
CN-110709405-B Silane containing benzothiazole, preparation method and application thereof 赢创运营有限公司 2022-07-26 CN disclosed
US-11254693-B2 Benzothiazole-containing silanes, method for the preparation and use thereof EVONIK OPERATIONS GMBH (DE) 2022-02-22 US disclosed
EP-3621972-B1 BENZOTHIAZOLE-CONTAINING SILANES, METHOD FOR THE PREPARATION AND USE THEREOF EVONIK OPERATIONS GMBH (DE) 2021-03-17 EP disclosed
CN-106967103-B Silicon-containing azodicarboxamides, their preparation and use 赢创运营有限公司 2020-10-30 CN disclosed
EP-3621972-A1 BENZOTHIAZOLE-CONTAINING SILANES, METHOD FOR THE PREPARATION AND USE THEREOF Evonik Operations GmbH (DE) 2020-03-18 EP disclosed
US-20200048285-A1 BENZOTHIAZOLE-CONTAINING SILANES, METHOD FOR THE PREPARATION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2020-02-13 US disclosed
CN-110709405-A Silane containing benzothiazole, preparation method and application thereof 赢创运营有限公司 2020-01-17 CN disclosed
CN-105001252-B Azocarbonyl-functionalized silanes 赢创德固赛有限公司 2019-12-24 CN disclosed
EP-3181571-B1 SILICON-CONTAINING AZODICARBOXAMIDES, THEIR PREPARATION AND USE EVONIK DEGUSSA GMBH (DE) 2019-07-24 EP disclosed
US-20070066760-A1 Organosilicon compounds their preparation and their use DEGUSSA AG (DE) 2007-03-22 US disclosed
US-20070049669-A1 Rubber mixtures EVONIK DEGUSSA GMBH (DE) 2007-03-01 US disclosed
EP-1754749-A2 Rubber mixtures Degussa AG (DE) 2007-02-21 EP disclosed
US-20060160935-A1 Mixture containing organosilicon compound DEGUSSA AG (DE) 2006-07-20 US disclosed
EP-1672017-A2 Rubber compositions Degussa GmbH (DE) 2006-06-21 EP disclosed
EP-0413504-B1 Rubber products and cure systems ROBINSON BROS LTD (GB) 1997-05-14 EP disclosed
US-5254635-A Sulfur-free vulcanization ROBINSON BROTHERS LIMITED (GB) 1993-10-19 US disclosed
EP-0413504-A1 Rubber products and cure systems ROBINSON BROTHERS LIMITED (GB) 1991-02-20 EP disclosed
EP-0284649-A1 Vulcanisation accelerator Firma Carl Freudenberg (DE) 1988-10-05 EP disclosed
EP-0284649-A1 Vulcanisation accelerator Firma Carl Freudenberg (DE) 1988-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066760-A1 Organosilicon compounds their preparation and their use MSH6, MCM6, SI MGLL 999/4885ALDH1A1 1519/4885ALDH2 1706/4885
US-11254693-B2 Benzothiazole-containing silanes, method for the preparation and use thereof SULT1A1, SULT1E1, SULT2A1 MGLL 4333/4885ALDH1A1 515/4885ALDH2 2186/4885
US-20200048285-A1 BENZOTHIAZOLE-CONTAINING SILANES, METHOD FOR THE PREPARATION AND USE THEREOF SULT1A1, SULT1E1, SULT2A1 MGLL 4333/4885ALDH1A1 515/4885ALDH2 2186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.