Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | APEX1 | P27695 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10586515 | 1.00 | LMNA (0.55) | LMNAAPEX1NPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31003437 | 1.00 | LMNA (0.55) | LMNAAPEX1NPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL667334 | 0.98 | LMNA (0.53) | LMNAAPEX1NPSR1MEN1KMT2A | |
| SCHEMBL1232505 | 0.97 | LMNA (0.57) | LMNAAPEX1NPSR1MEN1KMT2A | |
| Bromide SCHEMBL30494393 | 0.95 | LMNA (0.55) | LMNAAPEX1NPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10586518 | 0.95 | LMNA (0.55) | LMNAAPEX1NPSR1MEN1KMT2A | |
| Iodide SCHEMBL8679481 | 0.95 | LMNA (0.55) | LMNAAPEX1NPSR1MEN1KMT2A | |
| Water SCHEMBL3347894 | 0.95 | LMNA (0.55) | LMNAAPEX1NPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3421706 | 0.93 | LMNA (0.53) | LMNAAPEX1NPSR1MEN1KMT2A | |
| SCHEMBL18335664 | 0.89 | LMNA (0.50) | LMNAAPEX1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1570 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121060472-B | Composite modified montmorillonite for rare metal separation | 江西理工大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122011460-A | Preparation method of high-stability and high-conductivity composite anion exchange membrane | 安极能源(广东)有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-12595474-B2 | DNA data storage on two-dimensional support material | MICROSOFT TECHNOLOGY LICENSING, LLC (US) | 2026-04-07 | — | — | US | claimed |
| US-12564860-B2 | Coating process | BLUESCOPE STEEL LIMITED (AU) | 2026-03-03 | — | — | US | claimed |
| EP-4689041-A1 | CLEANING COMPOSITIONS AND METHODS OF USE THEREOF | FUJIFILM Electronic Materials U.S.A, Inc. (US) | 2026-02-11 | — | — | EP | claimed |
| EP-4688987-A1 | POLISHING COMPOSITIONS AND METHODS OF USE THEREOF | FUJIFILM Electronic Materials U.S.A, Inc. (US) | 2026-02-11 | — | — | EP | claimed |
| US-20260000623-A1 | DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES | CHAN, Hardy Wai Hong (TW) | 2026-01-01 | — | — | US | claimed |
| US-12496355-B2 | Method for treating a cancer and/or cancer metastasis | NANO TARGETING & THERAPY BIOPHARMA INC. (TW) | 2025-12-16 | — | — | US | claimed |
| EP-3368592-B1 | COSMETIC COMPOSITION, COSMETIC, AND EXTERNAL PREPARATION FOR SKIN | DOW TORAY CO LTD (JP) | 2025-12-03 | — | — | EP | claimed |
| US-20250277135-A1 | SILANE MODIFICATION OF CERIA NANOPARTICLES IN COLLOIDALLY STABLE SOLUTIONS | CMC MATERIALS LLC | 2025-09-04 | — | — | US | claimed |
| US-4992383-A | Method for protein and peptide sequencing using derivatized glass supports | PORTON INSTRUMENTS, INC. (US) | 1991-02-12 | — | — | US | claimed |
| EP-0389585-A1 | DERIVATIZED GLASS SUPPORTS FOR PEPTIDE AND PROTEIN SEQUENCING. | PORTON INSTR INC (US) | 1990-10-03 | — | — | EP | claimed |
| WO-1990001702-A1 | DERIVATIZED GLASS SUPPORTS FOR PEPTIDE AND PROTEIN SEQUENCING | PORTON INSTRUMENTS, INC. (US) | 1990-02-22 | — | — | WO | claimed |
| US-4701430-A | Hydrogenation catalyst and methods for its preparation and use to convert silicon tetrachloride to chlorosilane and silane | KOREA ADVANCE INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 1987-10-20 | — | — | US | claimed |
| US-4613491-A | Redistribution catalyst and methods for its preparation and use to convert chlorosilicon hydrides to silane | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1986-09-23 | — | — | US | claimed |
| US-4595602-A | Process for preparing overcoated electrophotographic imaging members | XEROX CORPORATION (US) | 1986-06-17 | — | — | US | claimed |
| EP-0179347-A2 | Hair conditioning compositions | Revlon, Inc. (US) | 1986-04-30 | — | — | EP | claimed |
| US-4567039-A | ORGANOSILICON QUATERNARY AMMONIUM SALT | REVLON, INC. (US) | 1986-01-28 | — | — | US | claimed |
| US-4552827-A | Planographic printing plate having cationic compound in interlayer | POLYCHROME CORP. (US) | 1985-11-12 | — | — | US | claimed |
| EP-0132379-A2 | Planographic printing plate | Polychrome Corporation (US) | 1985-01-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12564860-B2 | Coating process | SAMM50, PIGT, ITGA4 | ACHE 886/4885LMNA 461/4885APEX1 1902/4885 |
| US-20260000623-A1 | DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES | AQP4, ABCB1, SRMS | ACHE 319/4885LMNA 1004/4885APEX1 4090/4885 |
| US-12595474-B2 | DNA data storage on two-dimensional support material | DNMT3A, DNMT3L, DNMT3B | ACHE 3884/4885LMNA 364/4885APEX1 1576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.