SCHEMBL1206751

SCHEMBL1206751

CC(C)COc1cccc(CCC(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOS P01100 2/20 0.59
JUN P05412 2/20 0.59
FFAR1 O14842 11/20 0.57
FFAR4 Q5NUL3 3/20 0.52
PPARD Q03181 1/20 0.52
PPARG P37231 1/20 0.50
PPARA Q07869 1/20 0.50
FAAH O00519 1/20 0.49
NR1H4 Q96RI1 1/20 0.48
KEAP1 Q14145 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26203902 0.87 FOS (0.49) FOSJUNFFAR1PPARGPPARA
SCHEMBL6063476 0.85 FFAR1 (0.55) FOSJUNFFAR1FFAR4PPARD
SCHEMBL11805244 0.85 PLA2G4B (0.52) FOSJUNPPARDPPARGPPARA
Trifluoroacetic Acid SCHEMBL947972 0.83 KCNH2 (0.48) FOSJUNFFAR1FAAH
SCHEMBL1205628 0.83 FFAR4 (0.71) FFAR1FFAR4PPARDKEAP1
SCHEMBL1205963 0.83 FFAR1 (0.61) FFAR1FFAR4PPARDPPARGPPARA
SCHEMBL27018496 0.83 PPARA (0.48) FOSJUNPPARGPPARAFAAH
SCHEMBL23845448 0.82 PPARA (0.50) FOSJUNPPARGPPARAFAAH
SCHEMBL26203900 0.82 FOS (0.47) FOSJUNPPARGPPARAFAAH
SCHEMBL26229269 0.82 PPARA (0.50) FOSJUNPPARGPPARAFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
US-11253596-B2 Phenylalkylcarboxylic acid delivery agents NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) 2022-02-22 US claimed
US-20200405863-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS NOVO NORDISK A/S (DK) 2020-12-31 US claimed
EP-2114145-B1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS EMISPHERE TECH INC (US) 2017-11-01 EP claimed
US-20170189443-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS PLATINUM MONTAUR LIFE SCIENCES, LLC AND AS AGENT (KY) 2017-07-06 US claimed
CN-106456662-A Compositions of pentosan polysulfate for oral administration and methods of use thereof 奥利金制药公司 2017-02-22 CN claimed
EP-3110427-A1 COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE Urigen Pharmaceuticals, Inc. (US) 2017-01-04 EP claimed
CN-105233294-A Phenylalkylcarboxylic acid delivery agent EMISPHERE TECH INC 2016-01-13 CN claimed
WO-2015127416-A1 COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE URIGEN PHARMACEUTICALS, INC. (US) 2015-08-27 WO claimed
US-20120258911-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2012-10-11 US claimed
US-20110046050-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2011-02-24 US claimed
CN-101616583-A Phenylalkylcarboxylic acid delivery agents EMISPHERE TECH INC 2009-12-30 CN claimed
EP-2114145-A2 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS Emisphere Technologies, Inc. (US) 2009-11-11 EP claimed
WO-2008112368-A2 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2008-09-18 WO claimed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO disclosed
US-11253596-B2 Phenylalkylcarboxylic acid delivery agents NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) 2022-02-22 US disclosed
US-20200405863-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS NOVO NORDISK A/S (DK) 2020-12-31 US disclosed
EP-2114145-A2 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS Emisphere Technologies, Inc. (US) 2009-11-11 EP disclosed
WO-2008112368-A2 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2008-09-18 WO disclosed
WO-2008112368-A2 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2008-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200405863-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS PGF, LIPA, PDGFA FOS 1183/4885JUN 1429/4885FFAR1 713/4885
US-20110046050-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS PGF, LIPA, PDGFA FOS 1183/4885JUN 1429/4885FFAR1 713/4885
US-11253596-B2 Phenylalkylcarboxylic acid delivery agents PGF, LIPA, PDGFA FOS 1183/4885JUN 1429/4885FFAR1 713/4885
US-20170189443-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS SI, SLC20A1, SLC20A2 FOS 4045/4885JUN 4562/4885FFAR1 2107/4885
US-20120258911-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS PGF, LIPA, PDGFA FOS 1183/4885JUN 1429/4885FFAR1 713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.