Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12071697 | 0.88 | KDM4E (0.65) | KDM4EMAPTLMNATP53POLB | |
| SCHEMBL10483331 | 0.85 | KDM4E (0.57) | KDM4EMAPTLMNATP53POLB | |
| SCHEMBL12071695 | 0.85 | KDM4E (0.61) | KDM4EMAPTLMNATP53POLB | |
| SCHEMBL12070876 | 0.85 | KDM4E (0.61) | KDM4EMAPTLMNATP53POLB | |
| SCHEMBL12070862 | 0.83 | KDM4E (0.63) | KDM4EMAPTLMNATP53POLB | |
| SCHEMBL12070879 | 0.83 | KDM4E (0.62) | KDM4EMAPTLMNATP53POLB | |
| SCHEMBL12070878 | 0.83 | KDM4E (0.60) | KDM4EMAPTLMNATP53POLB | |
| SCHEMBL12070875 | 0.81 | KDM4E (0.56) | KDM4EMAPTLMNATP53POLB | |
| SCHEMBL10513812 | 0.78 | KDM4E (1.00) | KDM4EMAPTLMNATP53POLB | |
| SCHEMBL12072882 | 0.78 | HPGD (0.67) | KDM4EMAPTLMNATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10981876-B2 | Spiro compound and organic light emitting element comprising same | LG CHEM, LTD. | 2021-04-20 | — | — | US | disclosed |
| US-10580996-B2 | Polycyclic compound and organic light-emitting element comprising same | LG CHEM, LTD. (KR) | 2020-03-03 | — | — | US | disclosed |
| US-10577355-B2 | Hetero ring compound and organic luminescent element comprising same | LG CHEM, LTD. (KR) | 2020-03-03 | — | — | US | disclosed |
| US-10263193-B2 | Heterocyclic compound and organic light-emitting element using same | LG CHEM, LTD. (KR) | 2019-04-16 | — | — | US | disclosed |
| US-20180148640-A1 | DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-31 | — | — | US | disclosed |
| US-20180138421-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-17 | — | — | US | disclosed |
| US-20180138421-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-17 | — | — | US | disclosed |
| WO-2017034303-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | 주식회사 엘지화학 | 2017-03-02 | — | — | WO | disclosed |
| US-9273080-B2 | Metal complexes | MEREK PATENT GMBH (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9273080-B2 | Metal complexes | MEREK PATENT GMBH (DE) | 2016-03-01 | — | — | US | disclosed |
| US-20130082209-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-04-04 | — | — | US | disclosed |
| US-20130082209-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-04-04 | — | — | US | disclosed |
| WO-2011157339-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10263193-B2 | Heterocyclic compound and organic light-emitting element using same | CRY1, NFE2L2, CRY2 | KDM4E 2254/4885MAPT 1113/4885LMNA 2568/4885 |
| US-10981876-B2 | Spiro compound and organic light emitting element comprising same | RER1, RIF1, CRY1 | KDM4E 3645/4885MAPT 1866/4885LMNA 1310/4885 |
| US-20180138421-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | CRY2, NR2E3, CRY1 | KDM4E 1570/4885MAPT 530/4885LMNA 2374/4885 |
| US-10577355-B2 | Hetero ring compound and organic luminescent element comprising same | ORC3, CRY2, GLI1 | KDM4E 1232/4885MAPT 1446/4885LMNA 3118/4885 |
| US-20180148640-A1 | DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME | DCX, TERT, TELO2 | KDM4E 1392/4885MAPT 1276/4885LMNA 1895/4885 |
| US-20130082209-A1 | METAL COMPLEXES | MCOLN2, MCOLN1, AP1M1 | KDM4E 4129/4885MAPT 1164/4885LMNA 351/4885 |
| US-10580996-B2 | Polycyclic compound and organic light-emitting element comprising same | CRY2, NR2E3, CRY1 | KDM4E 1570/4885MAPT 530/4885LMNA 2374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.