Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.39 |
| ▸ | CA9 | Q16790 | 8/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27744847 | 0.75 | LMNA (0.46) | CA12CA9CA1CA2KDM4E | |
| SCHEMBL28483586 | 0.74 | LMNA (0.44) | CA12CA9CA1CA2KDM4E | |
| SCHEMBL24052575 | 0.72 | TK1 (0.55) | TK1 | |
| SCHEMBL27538958 | 0.72 | LMNA (0.52) | CA12CA9CA1CA2KDM4E | |
| SCHEMBL28687653 | 0.72 | LMNA (0.49) | CA12CA9CA1CA2KDM4E | |
| SCHEMBL27574601 | 0.70 | KDM4E (0.44) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL28457833 | 0.70 | LMNA (0.53) | CA12CA9CA1CA2KDM4E | |
| SCHEMBL11396309 | 0.68 | TK1 (0.50) | CA12CA9CA1CA2KDM4E | |
| SCHEMBL11098174 | 0.67 | TYMP (0.44) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL28661516 | 0.67 | SQOR (0.50) | KDM4ECYP1A2GRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2495243-B1 | NOVEL 5-FLUOROURACIL DERIVATIVE | DELTA-FLY PHARMA INC (JP) | 2016-12-28 | — | — | EP | disclosed |
| US-8889699-B2 | 5-fluorouracil derivative | DELTA-FLY PHARMA, INC. (JP) | 2014-11-18 | — | — | US | disclosed |
| US-20120232103-A1 | NOVEL 5-FLUOROURACIL DERIVATIVE | DELTA-FLY PHARMA, INC. (JP) | 2012-09-13 | — | — | US | disclosed |
| EP-2495243-A1 | NOVEL 5-FLUOROURACIL DERIVATIVE | Delta-Fly Pharma, Inc. (JP) | 2012-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232103-A1 | NOVEL 5-FLUOROURACIL DERIVATIVE | DPYD, FAU, MTHFD1 | CA12 3948/4885CA9 3687/4885CA1 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.