Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TK2 | O00142 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2635616 | 0.78 | MAPK1 (0.42) | TK1HPGDMAPK1 | |
| SCHEMBL17013802 | 0.77 | TK1 (0.59) | TK1HPGDRNASE1MAPK1TK2 | |
| SCHEMBL9391820 | 0.77 | HPGD (0.60) | TK1HPGDMAPK1DAOTK2 | |
| SCHEMBL8910349 | 0.76 | MAPK1 (0.41) | TK1HPGDMAPK1 | |
| SCHEMBL1418006 | 0.74 | TK1 (0.49) | TK1HPGDRNASE1MAPK1DAO | |
| SCHEMBL27482015 | 0.74 | POLB (0.46) | TSHR | |
| SCHEMBL12076397 | 0.72 | CA12 (0.39) | TK1 | |
| SCHEMBL4094755 | 0.72 | TK1 (0.63) | TK1HPGDMAPK1TK2 | |
| SCHEMBL8412383 | 0.72 | TYMP (0.43) | TK1HPGDMAPK1 | |
| SCHEMBL17016710 | 0.71 | TK1 (0.52) | TK1HPGDRNASE1MAPK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2021237223-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |