Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990731 | 0.80 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL13841487 | 0.80 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL12088713 | 0.79 | — | — | |
| SCHEMBL8234180 | 0.75 | ALDH1A1 (0.36) | — | |
| SCHEMBL13631881 | 0.74 | TGFBR1 (0.31) | — | |
| SCHEMBL2441528 | 0.74 | GRIK1 (0.46) | GRIK1GRIK2MAPK1 | |
| SCHEMBL26352875 | 0.74 | CA1 (0.32) | — | |
| SCHEMBL10061083 | 0.74 | CA1 (0.32) | — | |
| SCHEMBL22872306 | 0.74 | CA1 (0.32) | — | |
| SCHEMBL13227959 | 0.74 | TGFBR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748570-B2 | Insulin analogues | SYNGENE LIMITED (AU) | 2014-06-10 | — | — | US | disclosed |
| US-20120225811-A1 | INSULIN ANALOGUES | POLYCHIP PHARMACEUTICALS PTY LTD (AU) | 2012-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225811-A1 | INSULIN ANALOGUES | IAPP, INSR, GPR119 | GRIK1 3573/4885GRIK2 3066/4885MAPK1 2461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.