Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13841487 | 1.00 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL13841485 | 0.80 | TSHR (0.32) | — | |
| SCHEMBL8990796 | 0.80 | TSHR (0.32) | — | |
| SCHEMBL12088366 | 0.80 | GRIK1 (0.33) | GRIK1GRIK2 | |
| SCHEMBL18594672 | 0.75 | TGFBR1 (0.32) | — | |
| SCHEMBL2445753 | 0.75 | GRIK1 (0.36) | GRIK1GRIK2 | |
| SCHEMBL19398189 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL2441528 | 0.72 | GRIK1 (0.46) | GRIK1GRIK2 | |
| SCHEMBL19398277 | 0.72 | ALDH1A1 (0.31) | — | |
| SCHEMBL25524851 | 0.72 | CTSK (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102708-B2 | Methods for the synthesis of dicarba bridges in organic compounds | SYNGENE LIMITED (AU) | 2015-08-11 | — | — | US | disclosed |
| US-20130123463-A1 | METHODS FOR THE SYNTHESIS OF TWO OR MORE DICARBA BRIDGES IN ORGANIC COMPOUNDS | SYNGENE LIMITED (AU) | 2013-05-16 | — | — | US | disclosed |
| US-8362204-B2 | Methods for the synthesis of two or more dicarba bridges in organic compounds | SYNGENE LIMITED (AU) | 2013-01-29 | — | — | US | disclosed |
| US-8188217-B2 | — | — | 2012-05-29 | — | — | US | disclosed |
| US-20100036089-A1 | Methods for the Synthesis of Dicarba Bridges in Organic Compounds | MONASH UNIVERSITY (AU) | 2010-02-11 | — | — | US | disclosed |
| US-20090143565-A1 | Methods for the Synthesis of Two or More Dicarba Bridges in Organic Compounds | SYNGENE LIMITED (AU) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143565-A1 | Methods for the Synthesis of Two or More Dicarba Bridges in Organic Compounds | OTC, NBAS, IDH2 | GRIK1 3833/4885GRIK2 2584/4885 |
| US-20130123463-A1 | METHODS FOR THE SYNTHESIS OF TWO OR MORE DICARBA BRIDGES IN ORGANIC COMPOUNDS | OTC, NBAS, IDH2 | GRIK1 3833/4885GRIK2 2584/4885 |
| US-20100036089-A1 | Methods for the Synthesis of Dicarba Bridges in Organic Compounds | DCLRE1A, RNF168, MTCL3 | GRIK1 4229/4885GRIK2 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.