Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1325162 | 0.78 | CFD (0.33) | RXRATSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL1298306 | 0.75 | BLM (0.39) | TSHRHSD17B10ALDH1A1KDM4ERAB9A | |
| SCHEMBL14392624 | 0.71 | MEN1 (0.44) | ALDH1A1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL12104378 | 0.70 | RXRA (0.35) | RXRAHSD17B10ALDH1A1KDM4EMEN1 | |
| SCHEMBL3973917 | 0.67 | GLA (0.32) | RXRATSHRHSD17B10GABRPGABRD | |
| Pyromellitic Acid SCHEMBL21599248 | 0.67 | GABRP (0.42) | TSHRHSD17B10GABRPGABRDGABRA1 | |
| Pyromellitic Acid SCHEMBL15005172 | 0.67 | GABRP (0.42) | TSHRHSD17B10GABRPGABRDGABRA1 | |
| SCHEMBL3280425 | 0.66 | RXRA (0.33) | RXRATSHRHSD17B10GABRPGABRD | |
| SCHEMBL4116012 | 0.65 | GABRP (0.50) | RXRATSHRHSD17B10GABRPGABRD | |
| Pyromellitic Acid SCHEMBL27586566 | 0.63 | GABRP (0.39) | TSHRHSD17B10GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269716-A1 | ANTIOXIDANT COMPOUNDS AND METHODS OF THEIR USE | QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) | 2011-11-03 | — | — | US | disclosed |
| WO-2010037172-A1 | ANTIOXIDANT COMPOUNDS AND METHODS OF THEIR USE | QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269716-A1 | ANTIOXIDANT COMPOUNDS AND METHODS OF THEIR USE | NQO1, NFE2L2, GPX4 | RXRA 916/4885TSHR 4251/4885HSD17B10 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.