SCHEMBL3973917

SCHEMBL3973917

CCC1(CC)c2cc(C(=O)O)c(C(=O)O)cc2Oc2cc(C(=O)O)c(C(=O)O)cc21

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.32
ALOX5 P09917 1/20 0.32
RXRA P19793 2/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRB2 P47870 1/20 0.31
GABRA4 P48169 1/20 0.31
GABRE P78334 1/20 0.31
GABRA6 Q16445 1/20 0.31
GABRG1 Q8N1C3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3280425 0.84 RXRA (0.33) GLAALOX5RXRATSHRHSD17B10
SCHEMBL3272491 0.79 ALOX5 (0.34) ALOX5RXRASMN1; SMN2CYP2C9
SCHEMBL17238243 0.76 AKR1B1 (0.44) ALOX5RXRATSHRDAO
SCHEMBL29271883 0.73 SMN1; SMN2 (0.42) ALOX5TSHRHSD17B10SMN1; SMN2CYP2C9
SCHEMBL3471311 0.72 NOTUM (0.33) ALOX5RXRAHSD17B10
SCHEMBL3273061 0.71 POLB (0.40) TSHRHSD17B10SMN1; SMN2CYP2C9
SCHEMBL715286 0.71 ASPH (0.34) ALOX5RXRAHSD17B10SMN1; SMN2CYP2C9
SCHEMBL22901518 0.71 ALOX5 (0.32) ALOX5SMN1; SMN2CYP2C9
SCHEMBL3271333 0.71 ALOX5 (0.39) ALOX5RXRATSHRHSD17B10CYP2C9
SCHEMBL3274334 0.70 ALOX5 (0.41) GLAALOX5TSHRHSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760738-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor United States of America as represented by the Adminstrator of NASA (US) 2023-09-19 US disclosed
US-11725079-B2 Polyimide compositions and articles incorporating the same THE BOEING COMPANY (US) 2023-08-15 US disclosed
US-20220017697-A1 POLYIMIDE COMPOSITIONS AND ARTICLES INCORPORATING THE SAME UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 2022-01-20 US disclosed
US-20220017479-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2022-01-20 US disclosed
US-11130742-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2021-09-28 US disclosed
US-10808079-B2 Synthesis of copolyimides containing fluorine and silicon surface modifying agents UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2020-10-20 US disclosed
US-20200247770-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2020-08-06 US disclosed
US-10626098-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly (imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2020-04-21 US disclosed
US-9822088-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2017-11-21 US disclosed
WO-2016160512-A1 SYNTHESIS OF COPOLYIMIDES CONTAINING FLUORINE AND SILICON SURFACE MODIFYING AGENTS USA, as represented by the Administrator of the National Aeronautics and Space Administration (US) 2016-10-06 WO disclosed
US-20160280858-A1 Synthesis of Copolyimides Containing Fluorine and Silicon Surface Modifying Agents NATIONAL INSTITUTE OF AEROSPACE 2016-09-29 US disclosed
US-20120252968-A1 Anisotropic Copoly(imide Oxetane) Coatings and Articles of Manufacture, Copoly(imide Oxetane)s Containing Pendant Fluorocarbon Moieties, Oligomers and Processes Therefor U.S.A. AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2012-10-04 US disclosed
US-20090263640-A1 POLYCYCLIC POLYIMIDES AND COMPOSITIONS AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-10-22 US disclosed
US-20090226642-A1 LOW COLOR POLYIMIDE COMPOSITIONS USEFUL IN OPTICAL TYPE APPLICATIONS AND METHODS AND COMPOSITIONS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-10 US disclosed
US-7572878-B2 Showing improved thermal stability properties in conjunction with improved optical transparency making these polyimides useful in electronic device applications; replacement for quartz or glass in optical display devices or the like E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-11 US disclosed
US-7550194-B2 Low color polyimide compositions useful in optical type applications and methods and compositions relating thereto E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-23 US disclosed
EP-1764381-B1 Polycyclic polyimides and compositions and their corresponding polyamic acids DU PONT (US) 2008-06-18 EP disclosed
US-20080138537-A1 Low color polyimide compositions useful in optical type applications and methods and compositions relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2008-06-12 US disclosed
US-20070066734-A1 Polycyclic polyimides and compositions and methods relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2007-03-22 US disclosed
EP-1764381-A1 Polycyclic polyimides and compositions and their corresponding polyamic acids E.I.Du pont de nemours and company (US) 2007-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120252968-A1 Anisotropic Copoly(imide Oxetane) Coatings and Articles of Manufacture, Copoly(imide Oxetane)s Containing Pendant Fluorocarbon Moieties, Oligomers and Processes Therefor MACF1, OR51E2, EZR GLA 4810/4885ALOX5 2026/4885RXRA 4862/4885
US-11760738-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS GLA 4800/4885ALOX5 2145/4885RXRA 4860/4885
US-20200247770-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR MACF1, OR51E2, FOS GLA 4800/4885ALOX5 2145/4885RXRA 4860/4885
US-10626098-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly (imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS GLA 4800/4885ALOX5 2145/4885RXRA 4860/4885
US-11130742-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS GLA 4800/4885ALOX5 2145/4885RXRA 4860/4885
US-20220017479-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR MACF1, OR51E2, FOS GLA 4800/4885ALOX5 2145/4885RXRA 4860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.