SCHEMBL807580

SCHEMBL807580

CC1(C)CC2(CC(C)(C)c3cc4c(cc32)C(=O)OC4=O)c2cc3c(cc21)C(=O)OC3=O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22336440 0.87 CYP3A4 (0.43) ALDH1A1
SCHEMBL15665861 0.82 RXRA (0.41) ALDH1A1ALOX15TDP1
SCHEMBL8907843 0.81 RXRA (0.41) ALDH1A1TDP1
SCHEMBL30173380 0.75 FTO (0.34) ALDH1A1TDP1
SCHEMBL27200154 0.75 FTO (0.34) ALDH1A1TDP1
SCHEMBL16248003 0.75 ALDH1A1 (0.38) ALDH1A1ALOX15TDP1
SCHEMBL17320624 0.74 ALOX15 (0.42) ALDH1A1ALOX15TDP1
SCHEMBL22000345 0.74 ALDH1A1 (0.37) ALDH1A1ALOX15TDP1
SCHEMBL21166243 0.72 AHR (0.38)
SCHEMBL12758097 0.71 PPOX (0.39) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11289729-B2 Redox flow batteries and compounds for battery application THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2022-03-29 US disclosed
US-20200148825-A1 DIANHYDRIDES, POLYIMIDES DERIVED FROM BISCATECOL, METHODS OF MAKING, AND METHODS OF USE UNIV KING ABDULLAH SCI & TECH (SA) 2020-05-14 US disclosed
US-10604627-B2 Dianhydrides, polyimides derived from biscatecol, methods of making, and methods of use KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2020-03-31 US disclosed
US-20190185481-A1 TROGER'S BASE-BASED MONOMERS, AND POLYMERS, METHODS OF MAKING AND USES THEREOF UNIV KING ABDULLAH SCI & TECH (SA) 2019-06-20 US disclosed
US-9862801-B2 Polymers, their method of manufacture and use thereof THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2018-01-09 US disclosed
US-9845380-B2 Ionic polyimide materials and methods of use THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2017-12-19 US disclosed
US-9845380-B2 Ionic polyimide materials and methods of use THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2017-12-19 US disclosed
US-20160185909-A1 IONIC POLYIMIDE MATERIALS AND METHODS OF USE NATIONAL SCIENCE FOUNDATION 2016-06-30 US disclosed
US-20160185909-A1 IONIC POLYIMIDE MATERIALS AND METHODS OF USE NATIONAL SCIENCE FOUNDATION 2016-06-30 US disclosed
US-20160060396-A1 POLYMERS, THEIR METHOD OF MANUFACTURE AND USE THEREOF THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2016-03-03 US disclosed
US-20160060396-A1 POLYMERS, THEIR METHOD OF MANUFACTURE AND USE THEREOF THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2016-03-03 US disclosed
US-9212261-B2 Polymers, their method of manufacture and use thereof THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2015-12-15 US disclosed
US-9212261-B2 Polymers, their method of manufacture and use thereof THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2015-12-15 US disclosed
US-20130172433-A1 Polymers, Their Method of Manufacture and Use Thereof UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (UK) 2013-07-04 US disclosed
US-20130172433-A1 Polymers, Their Method of Manufacture and Use Thereof UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (UK) 2013-07-04 US disclosed
WO-2012035328-A1 POLYMERS, THEIR METHOD OF MANUFACTURE AND USE THEREOF UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2012-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200148825-A1 DIANHYDRIDES, POLYIMIDES DERIVED FROM BISCATECOL, METHODS OF MAKING, AND METHODS OF USE PAICS, CA13, FHIT ALDH1A1 971/4885ALOX15 3406/4885TDP1 740/4885
US-10604627-B2 Dianhydrides, polyimides derived from biscatecol, methods of making, and methods of use PAICS, CA13, FHIT ALDH1A1 971/4885ALOX15 3406/4885TDP1 740/4885
US-20190185481-A1 TROGER'S BASE-BASED MONOMERS, AND POLYMERS, METHODS OF MAKING AND USES THEREOF TRDMT1, TRMT1L, TRMT1 ALDH1A1 533/4885ALOX15 621/4885TDP1 112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.