Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13060052 | 1.00 | CYP1A2 (0.39) | CYP1A2CYP2C9ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12176000 | 0.89 | ALDH1A1 (0.45) | CYP1A2CYP2C9ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12176554 | 0.88 | TRPM8 (0.41) | CYP1A2CYP2C9ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12176555 | 0.87 | CYP1A2 (0.38) | CYP1A2CYP2C9ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12176320 | 0.86 | UBE2M (0.46) | ALDH1A1MAPTSMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL12176040 | 0.85 | CYP1A2 (0.36) | CYP1A2CYP2C9ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13060132 | 0.85 | ALDH1A1 (0.37) | CYP1A2CYP2C9ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12176304 | 0.85 | ALDH1A1 (0.37) | CYP1A2CYP2C9ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13059343 | 0.84 | CFD (0.49) | CYP2C9 | |
| SCHEMBL20879776 | 0.83 | ALDH1A1 (0.45) | CYP1A2CYP2C9ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275639-A1 | C5aR ANTAGONISTS | CHEMOCENTRYX, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-20100160320-A1 | C5aR ANTAGONISTS | CHEMOCENTRYX, INC. (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160320-A1 | C5aR ANTAGONISTS | C5AR1, C5AR2, C3AR1 | CYP1A2 2891/4885CYP2C9 2859/4885ALDH1A1 2966/4885 |
| US-20110275639-A1 | C5aR ANTAGONISTS | C5AR1, C5AR2, C3AR1 | CYP1A2 2891/4885CYP2C9 2859/4885ALDH1A1 2966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.