Cinnamic Aldehyde

Cinnamic Aldehyde

SCHEMBL121945

CCOC(C)OCC.O=C/C=C\c1ccccc1.OCC(O)CO

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
LMNA P02545 3/20 0.49
TRPA1 O75762 1/20 0.49
ALOX5 P09917 1/20 0.49
MAPK1 P28482 1/20 0.49
CCNB2 O95067 3/20 0.39
CDK1 P06493 3/20 0.39
CDK4 P11802 3/20 0.39
CCNB1 P14635 3/20 0.39
CCND1 P24385 3/20 0.39
CCNB3 Q8WWL7 3/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PPARA Q07869 4/20 0.36
PPARD Q03181 3/20 0.36
PPARG P37231 2/20 0.36
KDM4E B2RXH2 2/20 0.36
MAPT P10636 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinnamic Aldehyde SCHEMBL8740777 0.93 ALDH1A1 (0.50) ALDH1A1LMNATRPA1ALOX5MAPK1
Cinnamic Aldehyde SCHEMBL5515601 0.90 ALDH1A1 (0.53) ALDH1A1LMNATRPA1ALOX5MAPK1
Cinnamic Aldehyde SCHEMBL3159939 0.90 LMNA (0.60) ALDH1A1LMNATRPA1ALOX5MAPK1
Benzaldehyde SCHEMBL872657 0.86 ALDH1A1 (0.42) ALDH1A1LMNANPC1L3MBTL1PPARA
Cinnamaldehyde SCHEMBL2313727 0.85 ALDH1A1 (0.67) ALDH1A1LMNATRPA1ALOX5MAPK1
Cinnamaldehyde SCHEMBL2035468 0.85 ALDH1A1 (0.67) ALDH1A1LMNATRPA1ALOX5MAPK1
Cinnamaldehyde SCHEMBL1758311 0.83 ALDH1A1 (0.58) ALDH1A1LMNATRPA1ALOX5MAPK1
Cinnamic Aldehyde SCHEMBL11702441 0.82 ALDH1A1 (0.44) ALDH1A1LMNATRPA1ALOX5MAPK1
Cinnamic Aldehyde SCHEMBL8740823 0.82 ALDH1A1 (0.46) ALDH1A1LMNATRPA1ALOX5MAPK1
Benzaldehyde SCHEMBL17698491 0.81 ALDH1A1 (0.38) ALDH1A1LMNAL3MBTL1PPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1547 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11648298-B2 Oral care compositions COLGATE-PALMOLIVE COMPANY (US) 2023-05-16 US claimed
WO-2023046680-A1 COMBINATION OF CETYLPYRIDINIUM AND BENZYDAMINE WITH VIRUCIDAL EFFECT ON SARS-COV-2 KRKA, D.D., NOVO MESTO (SI) 2023-03-30 WO claimed
US-20210378920-A1 WET WIPER ARTICLES AND METHODS FOR CLEANING REMOVABLE DENTAL APPLIANCES Oral Health Technologies, LLC 2021-12-09 US claimed
US-11185479-B2 Buffered microencapsulated compositions and methods PREMIER DENTAL PRODUCTS COMPANY (US) 2021-11-30 US claimed
US-11185480-B2 Buffered microencapsulated compositions and methods PREMIER DENTAL PRODUCTS COMPANY (US) 2021-11-30 US claimed
US-20210228691-A1 Oral Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2021-07-29 US claimed
EP-3765036-A1 BUFFERED MICROENCAPSULATED COMPOSITIONS AND METHODS Premier Dental Products Company (US) 2021-01-20 EP claimed
US-10857075-B2 Wet wiper articles and methods for cleaning removable dental appliances Oral Health Technologies, LLC (US) 2020-12-08 US claimed
US-10688026-B2 Buffered microencapsulated compositions and methods PREMIER DENTAL PRODUCTS COMPANY (US) 2020-06-23 US claimed
US-10675227-B2 Buffered microencapsulated compositions and methods PREMIER DENTAL PRODUCTS COMPANY (US) 2020-06-09 US claimed
EP-0837862-A1 WARMING COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1998-04-29 EP claimed
US-5628986-A TOOTHPASTES, MOUTHRINSES, DENTIFRICES, LOZENGES, GUMS CONTAINING PHOSPHATE DERIVATIVE AND COPPER SOURCE THE PROCTER & GAMBLE COMPANY (US) 1997-05-13 US claimed
WO-1997002273-A1 WARMING COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1997-01-23 WO claimed
EP-0721323-A1 DIPHOSPHONIC ACID ESTERS AS TARTAR CONTROL AGENTS THE PROCTER & GAMBLE COMPANY (US) 1996-07-17 EP claimed
EP-0719128-A1 COMPOSITION CONTAINING PHOSPHATE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1996-07-03 EP claimed
EP-0719129-A1 PYROPHOSPHATE DIESTERS FOR TARTAR CONTROL THE PROCTER & GAMBLE COMPANY (US) 1996-07-03 EP claimed
WO-1996015768-A1 ORAL COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1996-05-30 WO claimed
WO-1995008979-A1 DIPHOSPHONIC ACID ESTERS AS TARTAR CONTROL AGENTS THE PROCTER & GAMBLE COMPANY (US) 1995-04-06 WO claimed
WO-1995007684-A1 PYROPHOSPHATE DIESTERS FOR TARTAR CONTROL THE PROCTER & GAMBLE COMPANY (US) 1995-03-23 WO claimed
WO-1995007683-A1 COMPOSITION CONTAINING PHOSPHATE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1995-03-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10688026-B2 Buffered microencapsulated compositions and methods LIPA, CHMP4B, APOB ALDH1A1 3890/4885LMNA 492/4885TRPA1 2805/4885
US-20210228691-A1 Oral Care Compositions LPO, LCT, MGAM ALDH1A1 2586/4885LMNA 1203/4885TRPA1 4084/4885
US-11185480-B2 Buffered microencapsulated compositions and methods CHMP4B, LIPA, APOB ALDH1A1 3804/4885LMNA 930/4885TRPA1 4140/4885
US-11648298-B2 Oral care compositions LPO, LCT, MGAM ALDH1A1 2586/4885LMNA 1203/4885TRPA1 4084/4885
US-10675227-B2 Buffered microencapsulated compositions and methods LIPA, CHMP4B, APOB ALDH1A1 3541/4885LMNA 688/4885TRPA1 3273/4885
US-11185479-B2 Buffered microencapsulated compositions and methods LIPA, CHMP4B, CRYAB ALDH1A1 3594/4885LMNA 2057/4885TRPA1 2505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.