Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | TET3 | O43151 | 4/20 | 0.52 |
| ▸ | FBXL19 | Q6PCT2 | 4/20 | 0.52 |
| ▸ | CXXC5 | Q7LFL8 | 4/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.52 |
| ▸ | CXXC4 | Q9H2H0 | 4/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.52 |
| ▸ | TET1 | Q8NFU7 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467789 | 0.73 | KMT2A (0.58) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL1447090 | 0.72 | OPRD1 (0.56) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL20385864 | 0.72 | SMN1; SMN2 (0.35) | KMT2AMEN1RAB9AKCNH2CYP2C19 | |
| SCHEMBL972474 | 0.69 | TSHR (0.65) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL119410 | 0.68 | KMT2A (0.49) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL23779147 | 0.67 | KMT2A (0.69) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL17187989 | 0.66 | KMT2A (0.52) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL3910173 | 0.66 | RORC (0.57) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL2702559 | 0.66 | KMT2A (0.68) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL11264109 | 0.65 | OPRM1 (0.55) | KMT2AMEN1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371366-A1 | Heterocyclo inhibitors of potassium channel function | Bristol-Myers Squibb Company (US) | 2011-10-05 | — | — | EP | disclosed |