Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12200280 | 0.83 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28809584 | 0.81 | CES2 (0.45) | CES2CES1EPHX2KIF11SRD5A2 | |
| SCHEMBL14438022 | 0.78 | SMN1; SMN2 (0.71) | SMN1; SMN2CES2CES1NR4A1NR4A2 | |
| SCHEMBL3597003 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2CES2CES1NR4A1NR4A2 | |
| SCHEMBL3149268 | 0.75 | LMNA (0.46) | SMN1; SMN2CES2CES1ALDH1A1LMNA | |
| SCHEMBL3150016 | 0.75 | LMNA (0.46) | SMN1; SMN2CES2CES1ALDH1A1LMNA | |
| SCHEMBL10863831 | 0.75 | CA2 (0.40) | ALDH1A1LMNAHTT | |
| SCHEMBL7020459 | 0.74 | SMN1; SMN2 (0.65) | SMN1; SMN2CES2CES1KIF11ALDH1A1 | |
| SCHEMBL28154008 | 0.74 | MAPT (0.50) | SMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL27712572 | 0.74 | NOTUM (0.41) | SMN1; SMN2CES2KIF11POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080166310-A1 | Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof | L'OREAL (FR) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080166310-A1 | Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof | KRT18, TYR, CRYAA | SMN1; SMN2 2913/4885CES2 3598/4885CES1 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.