SCHEMBL12200531

SCHEMBL12200531

CC1(C)OB(c2ccc3c(c2)-c2cccc4c(B5OC(C)(C)C(C)(C)O5)ccc-3c24)OC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 14/20 0.40
LPL P06858 13/20 0.40
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
IRAK4 Q9NWZ3 1/20 0.34
EGFR P00533 1/20 0.34
CA12 O43570 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL961673 0.88 KEAP1 (0.46) LIPGLPLPRMT5WDR77CRHBP
SCHEMBL29709221 0.88 KEAP1 (0.46) LIPGLPLPRMT5WDR77CRHBP
SCHEMBL30040842 0.88 KEAP1 (0.46) LIPGLPLPRMT5WDR77CRHBP
SCHEMBL12127199 0.84 ALDH1A1 (0.43) LIPGLPLPRMT5WDR77CRHBP
SCHEMBL13335834 0.84 LIPG (0.51) LIPGLPLPRMT5WDR77CRHBP
SCHEMBL11953434 0.83 LIPG (0.47) LIPGLPLCRHBPCRHR2KEAP1
SCHEMBL1637147 0.83 NPC1 (0.37) CRHBPCRHR2KEAP1NFE2L2
SCHEMBL15028119 0.83 NPC1 (0.37) CRHBPCRHR2KEAP1NFE2L2
SCHEMBL2229145 0.82 LIPG (0.48) LIPGLPLPRMT5WDR77CA1
SCHEMBL25263192 0.82 KEAP1 (0.43) LIPGLPLPRMT5WDR77CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8765270-B2 Triazine compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2014-07-01 US disclosed
US-8765270-B2 Triazine compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2014-07-01 US disclosed
EP-2016036-B1 FLUORANTHENE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME CANON KK (JP) 2014-06-04 EP disclosed
US-20110240983-A1 TRIAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-10-06 US disclosed
US-20110240983-A1 TRIAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-10-06 US disclosed
US-7737236-B2 Polymers based on fluoranthene and their use BASF AKTIENGESELLSCHAFT (DE) 2010-06-15 US disclosed
US-7737236-B2 Polymers based on fluoranthene and their use BASF AKTIENGESELLSCHAFT (DE) 2010-06-15 US disclosed
WO-2007126112-A1 FLUORANTHENE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2007-11-08 WO disclosed
EP-1345477-B1 Polymers based on fluoranthene and the use thereof BASF AG (DE) 2007-04-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110240983-A1 TRIAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME TERT, CYP1A1, NR2E3 LIPG 4717/4885LPL 3606/4885PRMT5 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.