SCHEMBL25263192

SCHEMBL25263192

CC1(C)OB(c2ccc(-c3ccc4c5c(cccc35)-c3ccccc3-4)c3ccccc23)OC1(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.43
NFE2L2 Q16236 2/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
PABPC1 P11940 2/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LPL P06858 4/20 0.37
LIPG Q9Y5X9 4/20 0.37
CASP1 P29466 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
MAPK1 P28482 2/20 0.35
HSD17B10 Q99714 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
HPGD P15428 1/20 0.35
HIF1A Q16665 1/20 0.35
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30040842 0.94 KEAP1 (0.46) KEAP1NFE2L2CRHBPCRHR2PABPC1
SCHEMBL961673 0.94 KEAP1 (0.46) KEAP1NFE2L2CRHBPCRHR2PABPC1
SCHEMBL29709221 0.94 KEAP1 (0.46) KEAP1NFE2L2CRHBPCRHR2PABPC1
SCHEMBL25273385 0.91 KEAP1 (0.43) KEAP1NFE2L2CRHBPCRHR2PABPC1
SCHEMBL16553054 0.90 LPL (0.41) KEAP1NFE2L2CRHBPCRHR2LPL
SCHEMBL16553033 0.88 LPL (0.44) LPLLIPGPRMT5WDR77JAK2
SCHEMBL18194212 0.88 LPL (0.44) LPLLIPGPRMT5WDR77JAK2
SCHEMBL20598426 0.88 CRHBP (0.38) KEAP1NFE2L2CRHBPCRHR2PABPC1
SCHEMBL16558494 0.86 KDM4E (0.43) KEAP1NFE2L2CRHBPCRHR2KDM4E
SCHEMBL31050212 0.86 LPL (0.39) MAPTKDM4ESMN1; SMN2LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230165140-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165140-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, TMEM109, TRPA1 KEAP1 695/4885NFE2L2 177/4885CRHBP 4745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.