Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 14/20 | 0.52 |
| ▸ | CHRNA10 | Q9GZZ6 | 5/20 | 0.52 |
| ▸ | CHRNA9 | Q9UGM1 | 5/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179433 | 0.91 | RELA (0.49) | PPARACHRNA7CHRNA10CHRNA9CHRNB4 | |
| SCHEMBL6179434 | 0.91 | RELA (0.49) | PPARACHRNA7CHRNA10CHRNA9CHRNB4 | |
| SCHEMBL1171656 | 0.84 | LTB4R (0.56) | PPARACHRNA7CHRNA10CHRNA9 | |
| SCHEMBL1171655 | 0.84 | LTB4R (0.56) | PPARACHRNA7CHRNA10CHRNA9 | |
| SCHEMBL13464287 | 0.80 | NR5A1 (0.54) | CHRNA7CHRNA10CHRNA9TP53 | |
| Phosphoric Acid SCHEMBL27998536 | 0.79 | PPARA (0.52) | PPARACHRNA7 | |
| SCHEMBL13639157 | 0.79 | KCNA3 (0.61) | ALDH1A1 | |
| SCHEMBL886955 | 0.77 | IDO1 (0.44) | PPARACHRNA7MEN1KMT2A | |
| SCHEMBL13639165 | 0.77 | KCNA3 (0.59) | — | |
| SCHEMBL4525962 | 0.77 | RELA (0.47) | PPARACHRNA7CHRNA10CHRNA9CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459727-A2 | BIOCATALYST FOR CATALYTIC HYDROAMINATION | BASF SE (DE) | 2012-06-06 | — | — | EP | claimed |
| US-20120123155-A1 | BIOCATALYST FOR CATALYTIC HYDROAMINATION | BASF SE (DE) | 2012-05-17 | — | — | US | claimed |
| WO-2011012632-A2 | BIOCATALYST FOR CATALYTIC HYDROAMINATION | BASF SE (DE) | 2011-02-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123155-A1 | BIOCATALYST FOR CATALYTIC HYDROAMINATION | HDHD5, PAH, GRHPR | PPARA 1880/4885CHRNA7 4798/4885CHRNA10 4777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.