SCHEMBL2097652

SCHEMBL2097652

O=C(O)Nc1ccccc1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.62
HPGD P15428 1/20 0.62
CYP2C19 P33261 1/20 0.62
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
NPC1 O15118 5/20 0.59
RAB9A P51151 5/20 0.59
KDM4E B2RXH2 2/20 0.58
POLB P06746 2/20 0.58
MAPT P10636 2/20 0.58
GAA P10253 1/20 0.58
MAPK1 P28482 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
EGFR P00533 1/20 0.58
MMP1 P03956 1/20 0.58
MMP2 P08253 1/20 0.58
MMP9 P14780 1/20 0.58
ALDH1A1 P00352 1/20 0.56
GPR55 Q9Y2T6 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL11753083 0.98 CYP1A2 (0.60) CYP1A2HPGDCYP2C19MEN1KMT2A
SCHEMBL6859262 0.84 CYP1A2 (0.64) CYP1A2HPGDCYP2C19MEN1KMT2A
SCHEMBL10458447 0.84 KDM4E (0.72) CYP1A2HPGDCYP2C19MEN1KMT2A
SCHEMBL5113547 0.84 MAPT (0.49) CYP1A2HPGDCYP2C19MEN1KMT2A
SCHEMBL1226530 0.83 SMN1; SMN2 (0.54) HPGDMEN1KMT2ANPC1RAB9A
SCHEMBL29519193 0.83 SMN1; SMN2 (0.54) HPGDMEN1KMT2ANPC1RAB9A
SCHEMBL8645476 0.83 GPR35 (0.68) CYP1A2HPGDCYP2C19MEN1KMT2A
SCHEMBL665304 0.83 MEN1 (0.69) HPGDMEN1KMT2ANPC1RAB9A
SCHEMBL2097649 0.82 CYP1A2 (0.62) CYP1A2HPGDCYP2C19MEN1KMT2A
SCHEMBL2175829 0.82 CYP1A2 (0.75) CYP1A2HPGDCYP2C19MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3011835-B1 Method for anti-sprouting tuber treatment with reduced amount of CIPC ARYSTA LIFESCIENCE BENELUX SPRL (BE) 2020-04-08 EP claimed
EP-2307024-B1 SUBSTITUTED CARBAMATE DERIVATIVES AS MODULATORS OF CORTICOTROPIN-RELEASING FACTOR RECEPTOR ACTIVITY BRISTOL MYERS SQUIBB CO (US) 2013-01-09 EP claimed
US-7655801-B2 Substituted carbamic acid quinolin-6-yl esters useful as acetylcholinesterase inhibitors COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2010-02-02 US claimed
EP-0820281-B1 A PHARMACEUTICAL COMPOSITION CONTAINING N-CHLOROPHENYLCARBAMATES AND N-CHLOROPHENYLTHIOCARBAMATES FOR INHIBITING THE GROWTH OF VIRUSES UAF TECHNOLOGIES AND RES LLC (US) 2007-07-25 EP claimed
US-20060142335-A1 Substituted carbamic acid quinolin-6-yl esters useful as acetylcholinesterase inhibitors COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2006-06-29 US claimed
US-20050239853-A1 New compounds BIOVITRUM AB (SE) 2005-10-27 US claimed
WO-2005075471-A2 THIAZOL-COMPOUNDS AS 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS BIOVITRUM AB (SE) 2005-08-18 WO claimed
US-20030149088-A1 HIV treatment UNIVERSITY OF ARIZONA FOUNDATION (US) 2003-08-07 US claimed
US-6498188-B1 ADMINISTRATING AN N-CHLOROPHENYLCARBAMATE OR AN N-CHLORO-PHENYLTHIOCARBAMATE IN COMBINATION WITH POTENTIATOR AND/OR CHEMOTHERAPEUTIC AGENT THE PROCTER & GAMBLE COMPANY 2002-12-24 US claimed
WO-2002041891-A2 HIV TREATMENT WITH BENZIMIDAZOLES THE PROCTER & GAMBLE COMPANY (US) 2002-05-30 WO claimed
US-20010041678-A1 Compositions and methods for treating cancer THE PROCTER & GAMBLE COMPANY 2001-11-15 US claimed
US-6251870-B1 COMPRISING A CHEMOTHERAPEUTIC AGENT SUCH AS METHOTREXATE AND AN N-CHLOROPHENYLCARBAMATE OR N-CHLOROPHENYLTHIOCARBAMATE OF GIVEN FORMULA THE PROCTER & GAMBLE COMPANY 2001-06-26 US claimed
US-20010002403-A1 N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions THE PROCTER & GAMBLE COMPANY 2001-05-31 US claimed
US-6177460-B1 USING A N-CHLOROPHENYL(THIO)CARBAMATE THE PROCTER & GAMBLE COMPANY 2001-01-23 US claimed
US-5932609-A Pharmaceutical composition for inhibiting the growth of cancers THE PROCTER & GAMBLE COMPANY (US) 1999-08-03 US claimed
US-5932604-A Pharmaceutical compositions for the treatment of viral infections THE PROCTER & GAMBLE COMPANY (US) 1999-08-03 US claimed
EP-0820282-A1 A PHARMACEUTICAL COMPOSITION CONTAINING N-CHLOROPHENYLCARBAMATES, N-CHLOROPHENYLTHIOCARBAMATES AND N-PHOSPHONOGLYCINE DERIVATIVES FOR INHIBITING THE GROWTH OF CANCERS AND VIRUSES IN MAMMALS THE PROCTER & GAMBLE COMPANY (US) 1998-01-28 EP claimed
EP-0820281-A1 A PHARMACEUTICAL COMPOSITION CONTAINING N-CHLOROPHENYLCARBAMATES AND N-CHLOROPHENYLTHIOCARBAMATES FOR INHIBITING THE GROWTH OF VIRUSES AND CANCERS THE PROCTER & GAMBLE COMPANY (US) 1998-01-28 EP claimed
WO-1996032103-A1 A PHARMACEUTICAL COMPOSITION CONTAINING N-CHLOROPHENYLCARBAMATES, N-CHLOROPHENYLTHIOCARBAMATES AND N-PHOSPHONOGLYCINE DERIVATIVES FOR INHIBITING THE GROWTH OF CANCERS AND VIRUSES IN MAMMALS THE PROCTER & GAMBLE COMPANY (US) 1996-10-17 WO claimed
WO-1996032104-A1 A PHARMACEUTICAL COMPOSITION CONTAINING N-CHLOROPHENYLCARBAMATES AND N-CHLOROPHENYLTHIOCARBAMATES FOR INHIBITING THE GROWTH OF VIRUSES AND CANCERS THE PROCTER & GAMBLE COMPANY (US) 1996-10-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050239853-A1 New compounds HSD11B1, CYP11B1, HSD3B1 CYP1A2 48/4885HPGD 66/4885CYP2C19 89/4885
US-20030149088-A1 HIV treatment BCOR, CYP3A4, NNT CYP1A2 267/4885HPGD 1595/4885CYP2C19 113/4885
US-20010002403-A1 N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions TP53, CPS1, MGMT CYP1A2 4552/4885HPGD 1950/4885CYP2C19 3246/4885
US-20010041678-A1 Compositions and methods for treating cancer HCCS, NTPCR, HMBS CYP1A2 3187/4885HPGD 1742/4885CYP2C19 1443/4885
US-20060142335-A1 Substituted carbamic acid quinolin-6-yl esters useful as acetylcholinesterase inhibitors ACHE, BCHE, NAAA CYP1A2 362/4885HPGD 2135/4885CYP2C19 612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.