Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYPLA1 | O75608 | 1/20 | 0.54 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12271034 | 0.80 | LYPLA1 (0.48) | LYPLA1LYPLA2TSHRCYP1A2CYP3A4 | |
| SCHEMBL12270835 | 0.80 | LYPLA1 (0.53) | LYPLA1LYPLA2TSHRCYP1A2CYP3A4 | |
| SCHEMBL18782421 | 0.78 | KDM4E (0.57) | LYPLA1LYPLA2TSHRCYP1A2CYP3A4 | |
| SCHEMBL12266342 | 0.78 | LYPLA1 (0.50) | LYPLA1LYPLA2MEN1KMT2AHTR1B | |
| SCHEMBL12270720 | 0.76 | LYPLA1 (0.49) | LYPLA1LYPLA2TSHRCYP1A2CYP3A4 | |
| SCHEMBL12266290 | 0.74 | CYP1A2 (0.49) | LYPLA1LYPLA2TSHRCYP1A2CYP3A4 | |
| SCHEMBL12270597 | 0.73 | LYPLA1 (0.45) | LYPLA1LYPLA2HTR1B | |
| SCHEMBL1554914 | 0.71 | TSHR (0.73) | LYPLA1LYPLA2TSHRCYP1A2CYP3A4 | |
| SCHEMBL12266426 | 0.71 | KDM4E (0.42) | LYPLA1LYPLA2TSHRCYP1A2CYP3A4 | |
| SCHEMBL12266295 | 0.71 | LTA4H (0.51) | LYPLA1LYPLA2TSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017809-B2 | Bisboron compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-09-13 | — | — | US | disclosed |
| US-20100087645-A1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087645-A1 | NOVEL BISBORON COMPOUND | KCNMB4, CA2, NR0B2 | LYPLA1 4548/4885LYPLA2 4342/4885TSHR 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.