SCHEMBL12267948

SCHEMBL12267948

CCCCC(CC)CNc1cc(CC(CC)CCCC)c(O)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGAM1 P18669 2/20 0.41
BRCA1 P38398 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HIF1A Q16665 1/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
TSHR P16473 2/20 0.38
HTT P42858 2/20 0.38
GLA P06280 1/20 0.38
AURKA O14965 1/20 0.38
AURKB Q96GD4 1/20 0.38
NQO1 P15559 2/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
IGFBP3 P17936 1/20 0.35
MAPT P10636 2/20 0.35
CYP3A4 P08684 2/20 0.35
TTR P02766 1/20 0.35
CYP1A1 P04798 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12268014 0.87 P2RY4 (0.40) SMN1; SMN2ALDH1A1KDM4EL3MBTL1TSHR
SCHEMBL23349789 0.85 TSHR (0.34) ALDH1A1KDM4EL3MBTL1TSHRHTT
SCHEMBL2183224 0.84 AURKA (0.56) PGAM1BRCA1SMN1; SMN2HIF1AALDH1A1
SCHEMBL2339098 0.82 ALDH1A1 (0.45) PGAM1ALDH1A1KDM4EL3MBTL1TSHR
SCHEMBL29425649 0.82 ALDH1A1 (0.45) PGAM1ALDH1A1KDM4EL3MBTL1TSHR
SCHEMBL1898463 0.81 MEN1 (0.46) PGAM1BRCA1SMN1; SMN2HIF1AALDH1A1
SCHEMBL14843485 0.78 MEN1 (0.42) PGAM1ALDH1A1KDM4EL3MBTL1TSHR
SCHEMBL4654063 0.77 MAPT (0.50) PGAM1SMN1; SMN2ALDH1A1KDM4EL3MBTL1
SCHEMBL15603977 0.76 MAPT (0.45) BRCA1SMN1; SMN2ALDH1A1KDM4EL3MBTL1
SCHEMBL28137525 0.76 ALDH1A1 (0.39) SMN1; SMN2ALDH1A1KDM4EL3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346946-B1 IMPROVEMENTS IN RELATION TO ELECTROWETTING ELEMENTS AMAZON EUROPE HOLDING TECH SCS (LU) 2021-05-12 EP disclosed
EP-3158386-B1 DYE COMPOUND, FLUID CARRIER AND ELECTROWETTING APPARATUS AMAZON TECH INC (US) 2021-04-14 EP disclosed
EP-3158386-B1 DYE COMPOUND, FLUID CARRIER AND ELECTROWETTING APPARATUS AMAZON TECH INC (US) 2021-04-14 EP disclosed
US-10338372-B2 Carrier fluid compounds and dye compounds for electrowetting apparatus AMAZON TECHNOLOGIES, INC. (US) 2019-07-02 US disclosed
US-10338372-B2 Carrier fluid compounds and dye compounds for electrowetting apparatus AMAZON TECHNOLOGIES, INC. (US) 2019-07-02 US disclosed
EP-3313812-A1 METHOD OF PREPARING A 2-ALKYL-4-ALKYLAMINO-1-HYDROXY-9,10-ANTHRACENEDIONE Amazon Technologies Inc. (US) 2018-05-02 EP disclosed
EP-3158386-A2 DYE COMPOUND, FLUID CARRIER AND ELECTROWETTING APPARATUS Amazon Technologies, Inc. (US) 2017-04-26 EP disclosed
WO-2016207252-A1 METHOD OF PREPARING A 2-ALKYL-4-ALKYLAMINO-1-HYDROXY-9,10-ANTHRACENEDIONE AMAZON TECHNOLOGIES, INC. (US) 2016-12-29 WO disclosed
US-9272981-B1 Method of preparing a compound AMAZON TECHNOLOGIES, INC. (US) 2016-03-01 US disclosed
US-20150370062-A1 CARRIER FLUID COMPOUNDS AND DYE COMPOUNDS FOR ELECTROWETTING APPARATUS AMAZON TECHNOLOGIES, INC. 2015-12-24 US disclosed
US-20150370062-A1 CARRIER FLUID COMPOUNDS AND DYE COMPOUNDS FOR ELECTROWETTING APPARATUS AMAZON TECHNOLOGIES, INC. 2015-12-24 US disclosed
US-20150370062-A1 CARRIER FLUID COMPOUNDS AND DYE COMPOUNDS FOR ELECTROWETTING APPARATUS AMAZON TECHNOLOGIES, INC. 2015-12-24 US disclosed
US-8980141-B2 Electrowetting elements AMAZON TECHNOLOGIES, INC. (US) 2015-03-17 US disclosed
US-8980141-B2 Electrowetting elements AMAZON TECHNOLOGIES, INC. (US) 2015-03-17 US disclosed
US-20110226998-A1 ELECTROWETTING ELEMENTS LIQUAVISTA B.V. (NL) 2011-09-22 US disclosed
US-20110226998-A1 ELECTROWETTING ELEMENTS LIQUAVISTA B.V. (NL) 2011-09-22 US disclosed
WO-2010031860-A2 IMPROVEMENTS IN RELATION TO ELECTROWETTING ELEMENTS LIQUAVISTA B.V. (NL) 2010-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10338372-B2 Carrier fluid compounds and dye compounds for electrowetting apparatus SLC26A3, SLC26A4, AQP1 PGAM1 4586/4885BRCA1 4748/4885SMN1; SMN2 3695/4885
US-20150370062-A1 CARRIER FLUID COMPOUNDS AND DYE COMPOUNDS FOR ELECTROWETTING APPARATUS SLC26A3, SLC26A4, AQP1 PGAM1 4586/4885BRCA1 4748/4885SMN1; SMN2 3695/4885
US-20110226998-A1 ELECTROWETTING ELEMENTS PLD2, PTGDR2, PLA2R1 PGAM1 3999/4885BRCA1 2882/4885SMN1; SMN2 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.