Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853152 | 0.76 | GAA (0.31) | MAPTGAA | |
| SCHEMBL7855328 | 0.75 | GAA (0.33) | MAPTGAA | |
| SCHEMBL5048603 | 0.67 | GSK3B (0.61) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL10783521 | 0.67 | GSK3B (0.61) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL3081408 | 0.67 | GPR84 (0.33) | MAPTGAAMEN1BCHEPOLB | |
| SCHEMBL8274 | 0.67 | PARP1 (0.34) | MAPTGAAMEN1BCHEPOLB | |
| SCHEMBL5686105 | 0.67 | PARP1 (0.34) | MAPTGAAMEN1BCHEPOLB | |
| SCHEMBL6111542 | 0.67 | L3MBTL1 (0.30) | — | |
| Formaldehyde SCHEMBL28424513 | 0.67 | PARP1 (0.31) | — | |
| SCHEMBL4742301 | 0.66 | TRPA1 (0.50) | MAPTGAAKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757558-A4 | SCREENING METHODS FOR INTEGUMENTAL INFLAMMATION MODULATING AGENTS | ALZA CORP (US) | 1999-06-16 | — | — | EP | claimed |
| EP-0757558-A1 | SCREENING METHODS FOR INTEGUMENTAL INFLAMMATION MODULATING AGENTS | ALZA CORPORATION (US) | 1997-02-12 | — | — | EP | claimed |
| WO-1995027510-A1 | SCREENING METHODS FOR INTEGUMENTAL INFLAMMATION MODULATING AGENTS | ALZA CORPORATION (US) | 1995-10-19 | — | — | WO | claimed |
| EP-0462696-B1 | Novel pyrido [2,3-f][1,4] thiazepines and pyrido [3,2-b][1,5] benzothiazepines | ORTHO PHARMA CORP (US) | 1995-08-09 | — | — | EP | claimed |
| EP-0526495-A1 | 1,5-BENZOTHIAZEPINONE DERIVATIVES, THEIR PREPARATIONS AND PHARMACEUTICAL USE | ISTITUTO LUSO FARMACO D'ITALIA S.p.A. (IT) | 1993-02-10 | — | — | EP | claimed |
| EP-0462696-A1 | Novel pyrido [2,3-f][1,4] thiazepines and pyrido [3,2-b][1,5] benzothiazepines | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-12-27 | — | — | EP | claimed |
| EP-0324181-B1 | PROCESS FOR THE PREPARATION OF BENZOTHIAZEPINONE DERIVATIVES | BAYER AG (DE) | 1991-11-27 | — | — | EP | claimed |
| WO-1991017153-A1 | 1,5-BENZOTHIAZEPINONE DERIVATIVES, THEIR PREPARATIONS AND PHARMACEUTICAL USE | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1991-11-14 | — | — | WO | claimed |
| EP-0242265-B1 | 1,5-BENZOTHIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | SYNTHELABO (FR) | 1991-05-29 | — | — | EP | claimed |
| US-4948886-A | Process for the preparation of benzothiazepinone derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-08-14 | — | — | US | claimed |
| EP-0324181-A1 | Process for the preparation of benzothiazepinone derivatives | BAYER AG (DE) | 1989-07-19 | — | — | EP | claimed |
| EP-0320361-A1 | 3-Hydroxy-2-(4-methoxyphenyl)-5(2-methylaminoethyl)-2,3-dihydro-5H-1,5-benzothiazepin-4-one derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1989-06-14 | — | — | EP | claimed |
| EP-0242265-A1 | 1,5-Benzothiazepine derivatives, their preparation and their therapeutical use | SYNTHELABO (FR) | 1987-10-21 | — | — | EP | claimed |
| JP-2145564-A | — | — | None | — | — | JP | disclosed |
| US-12454502-B2 | Synthesis of deuterated aldehydes | ARIZONA BOARD OF REGENTS ON BEHALF OF ATHE UNIVERSITY OF ARIZONA (US) | 2025-10-28 | — | — | US | disclosed |
| CN-115990258-A | Use of GSK 3beta inhibitor in treating primary immune thrombocytopenia | 复旦大学附属金山医院(上海市金山区眼病防治所、上海市金山区核化伤害应急救治中心) | 2023-04-21 | — | — | CN | disclosed |
| EP-0267924-A1 | NITRIC ESTERS OF BENZOTHIAZEPINONES | BAUDET, Pierre (CH) | 1988-05-25 | — | — | EP | disclosed |
| US-4743599-A | CALCIUM ANTAGONIST, CARDIOVASCULAR DISORDERS | SYNTHELABO (FR) | 1988-05-10 | — | — | US | disclosed |
| WO-1987006934-A1 | NITRIC ESTERS OF BENZOTHIAZEPINONES | BAUDET PIERRE (CH) | 1987-11-19 | — | — | WO | disclosed |
| EP-0242265-A1 | 1,5-Benzothiazepine derivatives, their preparation and their therapeutical use | SYNTHELABO (FR) | 1987-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12454502-B2 | Synthesis of deuterated aldehydes | ADH1C, ADH1A, CBR1 | MAPT 4584/4885GAA 1604/4885KDM4E 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.