Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MELK | Q14680 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15104662 | 0.85 | RXRA (0.41) | SCN5AKDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL182400 | 0.81 | MAPKAPK2 (0.56) | MAPKAPK2MELKMAP4K4 | |
| SCHEMBL505301 | 0.80 | DRD1 (0.56) | SCN5AALDH1A1DRD1 | |
| SCHEMBL8630160 | 0.80 | MELK (0.65) | MAPKAPK2MELK | |
| SCHEMBL29266901 | 0.79 | ABL1 (0.51) | MAPKAPK2MELKRXRAGRIN1GRIN2B | |
| SCHEMBL1229201 | 0.77 | SCN5A (0.44) | SCN5ADRD1SCN1ASCN2A | |
| SCHEMBL716281 | 0.77 | KDM4E (0.39) | SCN5AKDM4EALDH1A1SMN1; SMN2DRD1 | |
| SCHEMBL23968014 | 0.77 | MELK (0.45) | MAPKAPK2SCN5AMELKRXRAGRIN1 | |
| SCHEMBL1230329 | 0.75 | PIP4K2A (0.51) | SCN5ADRD1 | |
| SCHEMBL97114 | 0.75 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9179681-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| US-9179681-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| US-9179681-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| EP-2461687-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-09-16 | — | — | EP | disclosed |
| EP-2461687-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-09-16 | — | — | EP | disclosed |
| US-20140148340-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-05-29 | — | — | US | disclosed |
| US-20140148340-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-05-29 | — | — | US | disclosed |
| US-20140148340-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-05-29 | — | — | US | disclosed |
| US-8680269-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-8680269-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-8680269-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20120172217-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120172217-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120172217-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-05 | — | — | US | disclosed |
| EP-2461687-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011017504-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
| WO-2011017504-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148340-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PLCG2 | MAPKAPK2 3370/4885SCN5A 3053/4885KDM4E 2354/4885 |
| US-20120172217-A1 | PESTICIDAL COMPOSITIONS | DDT, AADAC, ACHE | MAPKAPK2 4659/4885SCN5A 2695/4885KDM4E 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.