Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | RECQL | P46063 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA4 | P22748 | 2/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | FYN | P06241 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | MMP9 | P14780 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11005179 | 0.80 | ALOX15 (0.62) | ALDH1A1HPGDMAPTALOX15KDM4E | |
| SCHEMBL23250757 | 0.80 | DBH (0.46) | ALDH1A1HPGDMAPTALOX15KDM4E | |
| SCHEMBL4156620 | 0.80 | TRPA1 (0.50) | ALDH1A1HPGDMAPTALOX15KDM4E | |
| SCHEMBL9644468 | 0.80 | CXCR2 (0.52) | ALDH1A1HPGDMAPTALOX15KDM4E | |
| SCHEMBL344192 | 0.78 | ALDH1A1 (0.61) | ALDH1A1HPGDMAPTALOX15KDM4E | |
| SCHEMBL16431316 | 0.78 | DBH (0.44) | ALDH1A1HPGDMAPTALOX15KDM4E | |
| Catechol SCHEMBL2241272 | 0.77 | ALDH1A1 (0.83) | ALDH1A1HPGDMAPTALOX15KDM4E | |
| Catechol SCHEMBL367675 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTALOX15KDM4E | |
| Catechol SCHEMBL30944695 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTALOX15KDM4E | |
| Catechol SCHEMBL29352716 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113652374-B | Application of 7-hydroxy tropolone in preventing and treating crop verticillium wilt | 浙江大学 | 2023-03-07 | — | — | CN | claimed |
| EP-4021413-A1 | LIPOSOMAL TROPONOID COMPOUND FORMULATIONS | United States Government as Represented by The Department of Veterans Affairs (US) | 2022-07-06 | — | — | EP | claimed |
| CN-113652374-A | Application of 7-hydroxy tropolone in preventing and treating crop verticillium wilt | 浙江大学 | 2021-11-16 | — | — | CN | claimed |
| WO-2021041776-A1 | LIPOSOMAL TROPONOID COMPOUND FORMULATIONS | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2021-03-04 | — | — | WO | claimed |
| CN-111893053-A | Pseudomonas fluorescens 22G5 and application of active ingredient 7-hydroxy tropolone thereof in preventing and treating crop verticillium wilt | 浙江大学 | 2020-11-06 | — | — | CN | claimed |
| CN-106566782-B | One plant of pseudomonad for producing 7- hydroxy tropolone and its application | 武汉大学 | 2019-07-09 | — | — | CN | claimed |
| WO-2019118803-A1 | CHEMICAL ENTITIES FOR LYTIC ACTIVATION OF KSHV AND THERAPEUTIC TARGETING OF VIRAL ENZYMES/PROTEINS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2019-06-20 | — | — | WO | claimed |
| CN-106565448-B | A method of isolating and purifying 7- hydroxy tropolone from bacterial supernatant | 武汉大学 | 2019-04-12 | — | — | CN | claimed |
| US-20100152301-A1 | Treatment of Viral Infections | GOVERNMENT OF THE US, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-06-17 | — | — | US | claimed |
| EP-1976497-A2 | TREATMENT OF VIRAL INFECTIONS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-10-08 | — | — | EP | claimed |
| WO-2007065007-A9 | TREATMENT OF VIRAL INFECTIONS | US HEALTH (US) | 2007-09-13 | — | — | WO | claimed |
| WO-2007065007-A2 | TREATMENT OF VIRAL INFECTIONS | GOVERNMENT OF THE U.S.A., AS REPERSENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2007-06-07 | — | — | WO | claimed |
| EP-0267378-B1 | TROPOLONE DERIVATIVES AS AN ANTI-MYCOPLASMA AGENT | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-11-04 | — | — | EP | claimed |
| EP-0267378-A2 | Tropolone derivatives as an anti-mycoplasma agent | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1988-05-18 | — | — | EP | claimed |
| WO-2019195181-A9 | ANTIBODIES AND FRAGMENTS THEREOF THAT BIND HEPATITIS B VIRUS PROTEIN X | GILEAD SCIENCES, INC. (US) | 2023-07-06 | — | — | WO | disclosed |
| EP-3307256-B1 | HYDROXYLATED TROPOLONE INHIBITORS OF NUCLEOTIDYL TRANSFERASES IN HERPESVIRUS AND HEPATITIS B | UNIV SAINT LOUIS (US) | 2023-06-07 | — | — | EP | disclosed |
| CN-113652374-B | Application of 7-hydroxy tropolone in preventing and treating crop verticillium wilt | 浙江大学 | 2023-03-07 | — | — | CN | disclosed |
| US-4883758-A | Biologically pure culture of the microorganism Streptomycas tropolofaciens used for producing 3,7-dihydroxytropolone and antitumor use | BRISTOL-MYERS COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4833079-A | CULTURE OF STREPTOMYCES | BRISTOL-MYERS COMPANY (US) | 1989-05-23 | — | — | US | disclosed |
| EP-0267378-A2 | Tropolone derivatives as an anti-mycoplasma agent | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1988-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152301-A1 | Treatment of Viral Infections | CD4, TYMP, DUT | ALDH1A1 1004/4885HPGD 1380/4885MAPT 3059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.