Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.34 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1234811 | 0.87 | CFTR (0.42) | TDP1MAPTNOTUMALDH1A1KDM4E | |
| SCHEMBL9995316 | 0.82 | TDP1 (0.46) | TDP1MAPTNOTUMALDH1A1HSD17B10 | |
| SCHEMBL6927688 | 0.80 | TDP1 (0.44) | TDP1MAPTNOTUMALDH1A1HSD17B10 | |
| SCHEMBL22075502 | 0.80 | TDP1 (0.44) | TDP1MAPTNOTUMALDH1A1HSD17B10 | |
| SCHEMBL1230305 | 0.80 | NOTUM (0.39) | NOTUMALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL412257 | 0.80 | TAS2R14 (0.42) | NOTUMALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL422124 | 0.80 | TAS2R14 (0.46) | TDP1MAPTNOTUMALDH1A1HSD17B10 | |
| SCHEMBL29276544 | 0.78 | KDM4E (0.42) | NOTUMALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL21192829 | 0.78 | CLCN2 (0.42) | NOTUMALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL8491961 | 0.77 | NOTUM (0.41) | NOTUMALDH1A1HSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475646-B1 | 4-(3-ALKYLTHIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | BAYER IP GMBH (DE) | 2017-06-21 | — | — | EP | disclosed |
| EP-2816896-B1 | HERBICIDALLY ACTIVE SULFINIMIDOYL- AND SULFONIMIDOYLBENZOYL DERIVATIVES | BAYER IP GMBH (DE) | 2016-09-07 | — | — | EP | disclosed |
| EP-2817296-B1 | HERBICIDALLY ACTIVE 3-(SULFIN-/SULFONIMIDOYL)-BENZAMIDES | BAYER IP GMBH (DE) | 2016-08-31 | — | — | EP | disclosed |
| US-9167819-B2 | Herbicidal 3-(sulfin-/sulfonimidoyl)-benzamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-9156784-B2 | Herbicidal sulfinimidoyl- and sulfonimidoyl benzoyl derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-10-13 | — | — | US | disclosed |
| US-20150031536-A1 | HERBICIDAL SULFINIMIDOYL- AND SULFONIMIDOYL BENZOYL DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-01-29 | — | — | US | disclosed |
| EP-2817296-A1 | HERBICIDAL 3 - ( SULFIN- /SULFONIMIDOYL) - BENZAMIDES | Bayer Intellectual Property GmbH (DE) | 2014-12-31 | — | — | EP | disclosed |
| EP-2816896-A1 | HERBICIDAL SULFINIMIDOYL- AND SULFONIMIDOYL BENZOYL DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013124230-A1 | HERBICIDAL SULFINIMIDOYL- AND SULFONIMIDOYL BENZOYL DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-29 | — | — | WO | disclosed |
| WO-2013124228-A1 | HERBICIDAL 3 - ( SULFIN- /SULFONIMIDOYL) - BENZAMIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-29 | — | — | WO | disclosed |
| EP-2459528-B1 | 2-(3-ALKYLTHIOBENZOYL)CYCLOHEXANEDIONES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2013-05-15 | — | — | EP | disclosed |
| US-8288319-B2 | 4-(3-alkylthiobenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2012-10-16 | — | — | US | disclosed |
| EP-2475646-A1 | 4-(3-ALKYLTHIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | Bayer CropScience AG (DE) | 2012-07-18 | — | — | EP | disclosed |
| EP-2459528-A1 | 2-(3-ALKYLTHIOBENZOYL)CYCLOHEXANEDIONES AND THEIR USE AS HERBICIDES | Bayer CropScience AG (DE) | 2012-06-06 | — | — | EP | disclosed |
| US-8193121-B2 | 2-(3-alkylthiobenzoyl)cyclohexanediones and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2012-06-05 | — | — | US | disclosed |
| US-20110053779-A1 | 2-(3-ALKYLTHIOBENZOYL)CYCLOHEXANEDIONES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-03-03 | — | — | US | disclosed |
| US-20110045980-A1 | 4-(3-ALKYLTHIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-02-24 | — | — | US | disclosed |
| WO-2011012246-A1 | 4-(3-ALKYLTHIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-02-03 | — | — | WO | disclosed |
| WO-2011012247-A1 | 2-(3-ALKYLTHIOBENZOYL)CYCLOHEXANEDIONES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053779-A1 | 2-(3-ALKYLTHIOBENZOYL)CYCLOHEXANEDIONES AND THEIR USE AS HERBICIDES | DDT, CBR3, CYP1B1 | TDP1 1678/4885MAPT 4683/4885NOTUM 1410/4885 |
| US-20110045980-A1 | 4-(3-ALKYLTHIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | CYP4X1, PRDX4, PRXL2A | TDP1 1707/4885MAPT 4199/4885NOTUM 2059/4885 |
| US-20150031536-A1 | HERBICIDAL SULFINIMIDOYL- AND SULFONIMIDOYL BENZOYL DERIVATIVES | SQOR, PRDX1, PRDX4 | TDP1 3457/4885MAPT 4826/4885NOTUM 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.