Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.31 |
| ▸ | ITGAV | P06756 | 10/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 8/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402038 | 1.00 | HRH3 (0.36) | HRH3ITGB3ITGAVITGB5HDAC8 | |
| SCHEMBL12910759 | 1.00 | HRH3 (0.36) | HRH3ITGB3ITGAVITGB5HDAC8 | |
| SCHEMBL4399713 | 0.89 | HRH3 (0.32) | HRH3 | |
| SCHEMBL12910736 | 0.84 | HDAC8 (0.39) | HRH3ITGB3ITGAVHDAC8 | |
| SCHEMBL13078421 | 0.84 | HRH3 (0.35) | HRH3ITGB3ITGAV | |
| SCHEMBL12019159 | 0.84 | HRH3 (0.37) | HRH3ITGB3ITGAV | |
| SCHEMBL4399717 | 0.83 | ITGB3 (0.41) | HRH3ITGB3ITGAVITGB5HDAC8 | |
| SCHEMBL12019149 | 0.83 | ITGB3 (0.41) | HRH3ITGB3ITGAVITGB5HDAC8 | |
| SCHEMBL16840265 | 0.83 | ITGB3 (0.41) | HRH3ITGB3ITGAVITGB5HDAC8 | |
| SCHEMBL15762025 | 0.83 | ITGB3 (0.41) | HRH3ITGB3ITGAVITGB5HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2937334-B1 | PROPIONIC ACIDS, PROPIONIC ACID ESTERS, AND RELATED COMPOUNDS | PROMENTIS PHARM INC (US) | 2017-04-19 | — | — | EP | disclosed |
| EP-2937334-A1 | PROPIONIC ACIDS, PROPIONIC ACID ESTERS, AND RELATED COMPOUNDS | Promentis Pharmaceuticals, Inc. (US) | 2015-10-28 | — | — | EP | disclosed |
| US-8815905-B2 | Propionic acids, propionic acid esters, and related compounds | PROMENTIS PHARMACEUTICALS, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8435997-B2 | Cysteine prodrugs to treat schizophrenia and drug addiction | MARQUETTE UNIVERSITY (US) | 2013-05-07 | — | — | US | disclosed |
| US-8435997-B2 | Cysteine prodrugs to treat schizophrenia and drug addiction | MARQUETTE UNIVERSITY (US) | 2013-05-07 | — | — | US | disclosed |
| US-20110224156-A1 | Propionic Acids, Propionic Acid Esters, and Related Compounds | ALBANY MOLECULAR RESEARCH, INC. | 2011-09-15 | — | — | US | disclosed |
| US-20110021533-A1 | CYSTEINE PRODRUGS TO TREAT SCHIZOPHRENIA AND DRUG ADDICTION | MARQUETTE UNIVERSITY (US) | 2011-01-27 | — | — | US | disclosed |
| US-20110021533-A1 | CYSTEINE PRODRUGS TO TREAT SCHIZOPHRENIA AND DRUG ADDICTION | MARQUETTE UNIVERSITY (US) | 2011-01-27 | — | — | US | disclosed |
| US-7829709-B1 | Cysteine prodrugs to treat schizophrenia and drug addiction | MARQUETTE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |
| US-7829709-B1 | Cysteine prodrugs to treat schizophrenia and drug addiction | MARQUETTE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224156-A1 | Propionic Acids, Propionic Acid Esters, and Related Compounds | PCCA, PC, PMP22 | HRH3 1019/4885ITGB3 3534/4885ITGAV 4030/4885 |
| US-20110021533-A1 | CYSTEINE PRODRUGS TO TREAT SCHIZOPHRENIA AND DRUG ADDICTION | CTH, CBS, SLC6A3 | HRH3 3124/4885ITGB3 3980/4885ITGAV 3793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.