Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | STAT3 | P40763 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAS2R46 | P59540 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18316481 | 0.97 | LMNA (0.60) | LMNACYP3A4ALOX15PTPN1MAPK1 | |
| SCHEMBL12663607 | 0.97 | LMNA (0.60) | LMNACYP3A4ALOX15PTPN1MAPK1 | |
| SCHEMBL580624 | 0.97 | LMNA (0.60) | LMNACYP3A4ALOX15PTPN1MAPK1 | |
| SCHEMBL25380943 | 0.88 | LMNA (0.57) | LMNACYP3A4ALOX15PTPN1MAPK1 | |
| SCHEMBL25380939 | 0.86 | LMNA (0.59) | LMNACYP3A4ALOX15PTPN1MAPK1 | |
| SCHEMBL15470540 | 0.82 | LMNA (0.51) | LMNACYP3A4ALOX15PTPN1MAPK1 | |
| SCHEMBL27843244 | 0.82 | LMNA (0.52) | LMNACYP3A4ALOX15PTPN1MAPK1 | |
| SCHEMBL16553105 | 0.82 | LMNA (0.54) | LMNACYP3A4ALOX15PTPN1MAPK1 | |
| SCHEMBL19919389 | 0.82 | LMNA (0.54) | LMNACYP3A4ALOX15PTPN1MAPK1 | |
| SCHEMBL17389214 | 0.81 | LMNA (0.53) | LMNACYP3A4ALOX15PTPN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210115357-A1 | Fabric Treatment Method for Stain Release | VAN BUSKIRK GREGORY (US) | 2021-04-22 | — | — | US | disclosed |
| US-10900168-B2 | Fabric treatment for stain repellency | van Buskirk, Gregory (US) | 2021-01-26 | — | — | US | disclosed |
| US-10822577-B2 | Fabric treatment method for stain release | VAN BUSKIRK GREGORY (US) | 2020-11-03 | — | — | US | disclosed |
| US-20200318284-A1 | Laundry Additive for Providing Antimicrobial Effects to Fabrics and Interior Surfaces of Washing Machines | VAN BUSKIRK GREGORY (US) | 2020-10-08 | — | — | US | disclosed |
| US-10577743-B2 | Laundry additive for providing antimicrobial effects to fabrics and interior surfaces of washing machine | VAN BUSKIRK GREGORY (US) | 2020-03-03 | — | — | US | disclosed |
| US-10334853-B2 | Compositions and methods for treating ectoparasite infestation | Larada Sciences (US) | 2019-07-02 | — | — | US | disclosed |
| US-20180327696-A1 | FABRIC TREATMENT METHOD FOR STAIN RELEASE | VAN BUSKIRK GREGORY (US) | 2018-11-15 | — | — | US | disclosed |
| US-20180298552-A9 | Laundry Additive for Providing Antimicrobial Effects to Fabrics and Washing Machine Surfaces | VAN BUSKIRK GREGORY (US) | 2018-10-18 | — | — | US | disclosed |
| EP-3365418-A2 | PARTICLES FOR MALODOR REDUCTION | The Procter and Gamble Company (US) | 2018-08-29 | — | — | EP | disclosed |
| EP-3307393-A1 | FRAGRANCE COMPOSITION | The Procter and Gamble Company (US) | 2018-04-18 | — | — | EP | disclosed |
| WO-2011056935-A1 | DELIVERY PARTICLE | THE PROCTER & GAMBLE COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |
| US-7893014-B2 | Using hydrophobic agent having melting point or glass transition temperature of less than 100 degrees C and zeta potential modifier so that composition has zeta potential that is positive and greater than zero millivolts, curing; may also include a fluoropolymer; kits | GREGORY VAN BUSKIRK (US) | 2011-02-22 | — | — | US | disclosed |
| US-20080148491-A1 | Fabric Treatment For Stain Release | VAN BUSKIRK, GREGORY | 2008-06-26 | — | — | US | disclosed |
| US-20070256252-A1 | Fabric Treatment for Stain Release | CASELLA VICTOR M | 2007-11-08 | — | — | US | disclosed |
| US-20050229327-A1 | Fabric treatment for stain release | THE CLOROX COMPANY | 2005-10-20 | — | — | US | disclosed |
| US-20050204477-A1 | Fabric treatment for stain release | VAN BUSKIRK, GREGORY | 2005-09-22 | — | — | US | disclosed |
| US-20050166333-A1 | Fabric treatment for stain release | THE CLOROX COMPANY | 2005-08-04 | — | — | US | disclosed |
| WO-2004063318-A1 | FABRIC TREATMENT FOR STAIN RELEASE | THE CLOROX COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |
| US-20030192130-A1 | Fabric treatment for stain release | VAN BUSKIRK, GREGORY | 2003-10-16 | — | — | US | disclosed |
| US-6211139-B1 | Polyester polyquaternary compounds, compositions containing them, and use thereof | GOLDSCHMIDT CHEMICAL CORPORATION | 2001-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200318284-A1 | Laundry Additive for Providing Antimicrobial Effects to Fabrics and Interior Surfaces of Washing Machines | CUTA, MGLL, POLL | LMNA 1202/4885CYP3A4 1020/4885ALOX15 732/4885 |
| US-10577743-B2 | Laundry additive for providing antimicrobial effects to fabrics and interior surfaces of washing machine | CUTA, MGLL, CD68 | LMNA 1276/4885CYP3A4 1091/4885ALOX15 751/4885 |
| US-20180298552-A9 | Laundry Additive for Providing Antimicrobial Effects to Fabrics and Washing Machine Surfaces | CUTA, MGLL, POLL | LMNA 966/4885CYP3A4 1237/4885ALOX15 460/4885 |
| US-10334853-B2 | Compositions and methods for treating ectoparasite infestation | POLR1C, ATP6V0C, EXOSC5 | LMNA 3865/4885CYP3A4 2287/4885ALOX15 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.