Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71266 | 1.00 | OPRD1 (0.54) | OPRD1OPRM1ALDH1A1HPGDKMT2A | |
| SCHEMBL12360012 | 0.87 | OPRD1 (0.53) | OPRD1OPRM1ALDH1A1HPGDKMT2A | |
| SCHEMBL1934353 | 0.87 | OPRD1 (0.53) | OPRD1OPRM1ALDH1A1HPGDKMT2A | |
| SCHEMBL1142916 | 0.84 | L3MBTL1 (0.52) | ALDH1A1HPGDKMT2AMEN1L3MBTL1 | |
| SCHEMBL6936409 | 0.81 | OPRD1 (0.52) | OPRD1OPRM1ALDH1A1HPGDMAPT | |
| SCHEMBL3107154 | 0.81 | OPRD1 (0.51) | OPRD1OPRM1ALDH1A1HPGDMAPT | |
| SCHEMBL11362571 | 0.80 | OPRM1 (0.65) | OPRD1OPRM1ALDH1A1HPGDKMT2A | |
| SCHEMBL4576604 | 0.80 | ALDH1A1 (0.65) | OPRD1OPRM1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8527824 | 0.80 | HPGD (0.58) | OPRD1OPRM1ALDH1A1HPGDKMT2A | |
| SCHEMBL4830938 | 0.80 | HPGD (0.54) | OPRD1OPRM1ALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207745-A1 | SOLID FORMS OF 4--N,N-DIETHYLBENZAMIDE, COMPOSITIONS THEREOF, AND USES THEREWITH | ASTRAZENECA AB (SE) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207745-A1 | SOLID FORMS OF 4--N,N-DIETHYLBENZAMIDE, COMPOSITIONS THEREOF, AND USES THEREWITH | VHL, TPMT, NNMT | OPRD1 4300/4885OPRM1 3133/4885ALDH1A1 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.