Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12366188 | 0.82 | LMNA (0.47) | ALDH1A1KMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL12366142 | 0.82 | KMT2A (0.59) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL12366100 | 0.82 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL13652539 | 0.80 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL18232498 | 0.79 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL12019235 | 0.79 | HPGD (0.71) | ALDH1A1L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL12366135 | 0.79 | LMNA (0.62) | ALDH1A1KMT2ARAB9ASMN1; SMN2CA12 | |
| SCHEMBL12366096 | 0.79 | L3MBTL1 (0.57) | ALDH1A1L3MBTL1MEN1KMT2ACA12 | |
| SCHEMBL11591975 | 0.78 | GAA (0.59) | ALDH1A1L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL12366192 | 0.78 | EPHX2 (0.54) | ALDH1A1L3MBTL1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |