Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14941327 | 0.81 | CHRM2 (0.35) | SLC18A3ALDH1A1LTA4HCHRM2CHRM4 | |
| SCHEMBL1098014 | 0.77 | NCF1 (0.48) | SLC18A3ALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL20851287 | 0.77 | SLC18A3 (0.37) | SLC18A3ALDH1A1LTA4HCHRM2CHRM4 | |
| SCHEMBL12284377 | 0.77 | SLC18A3 (0.37) | SLC18A3ALDH1A1LTA4HCHRM2CHRM4 | |
| SCHEMBL1543625 | 0.77 | CYP1A2 (0.38) | SLC18A3ALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL79852 | 0.77 | — | — | |
| SCHEMBL1103885 | 0.77 | GPR119 (0.48) | SLC18A3LTA4HCHRM2CHRM4CHRM5 | |
| SCHEMBL8054785 | 0.76 | CHRM2 (0.46) | SLC18A3ALDH1A1LTA4HCHRM2CHRM4 | |
| SCHEMBL15047082 | 0.75 | — | — | |
| SCHEMBL863016 | 0.75 | ITGB3 (0.50) | ALDH1A1LTA4HHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190263-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-08-04 | — | — | US | disclosed |
| US-20100022515-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190263-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR65, GPR39 | SLC18A3 526/4885ALDH1A1 1462/4885LTA4H 599/4885 |
| US-20100022515-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GCGR, GPR65 | SLC18A3 1700/4885ALDH1A1 2253/4885LTA4H 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.