Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 9/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.40 |
| ▸ | WNT1 | P04628 | 7/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12367652 | 0.83 | KDM4E (0.42) | KDM4ESMN1; SMN2GSK3BDYRK1AWNT1 | |
| SCHEMBL12367648 | 0.79 | TACR3 (0.41) | KDM4ESMN1; SMN2GSK3BDYRK1AWNT1 | |
| SCHEMBL507523 | 0.73 | P4HTM (0.40) | KDM4EKMT2AHRH3CYP2C9 | |
| SCHEMBL18595333 | 0.70 | TDP1 (0.46) | KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL24724937 | 0.69 | NAMPT (0.47) | KDM4ESMN1; SMN2GSK3BDYRK1AWNT1 | |
| SCHEMBL8096313 | 0.69 | LMNA (0.60) | KMT2A | |
| SCHEMBL2642680 | 0.68 | L3MBTL1 (0.46) | KDM4ESMN1; SMN2KMT2ACYP2C9 | |
| SCHEMBL15531288 | 0.68 | PARP2 (0.38) | KDM4ESMN1; SMN2GSK3BDYRK1AWNT1 | |
| SCHEMBL4732168 | 0.67 | SMN1; SMN2 (0.63) | KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL2642696 | 0.67 | P4HTM (0.46) | KDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207734-A1 | Azine Derivatives and Methods of Use Thereof | PALANI ANANDAN | 2011-08-25 | — | — | US | disclosed |
| US-20110207734-A1 | Azine Derivatives and Methods of Use Thereof | PALANI ANANDAN | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207734-A1 | Azine Derivatives and Methods of Use Thereof | AZI2, GPR119, GID4 | KDM4E 1411/4885SMN1; SMN2 1993/4885GSK3B 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.