SCHEMBL12367662

SCHEMBL12367662

C=C1C(C)C(C)C(=O)N1c1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.46
HSP90AA1 P07900 1/20 0.46
PKM P14618 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MGLL Q99685 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
KMT2A Q03164 2/20 0.42
APAF1 O14727 1/20 0.42
POLB P06746 1/20 0.42
ESR1 P03372 8/20 0.40
ESR2 Q92731 7/20 0.40
RAB9A P51151 2/20 0.37
NR1H3 Q13133 1/20 0.36
CAPN1 P07384 1/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 2/20 0.35
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9923585 0.87 MAPK1 (0.54) MAPK1HSP90AA1PKMNPSR1MGLL
SCHEMBL16601565 0.81 MAOA (0.49) MGLLKMT2APOLBALDH1A1MAPT
SCHEMBL26499186 0.76 HSP90AA1 (0.47) MAPK1HSP90AA1PKMNPSR1MGLL
SCHEMBL26498944 0.76 HSP90AA1 (0.47) MAPK1HSP90AA1PKMNPSR1MGLL
SCHEMBL13753295 0.76 RAB9A (0.53) MGLLKMT2ARAB9ATP53MEN1
SCHEMBL13198797 0.69 RAB9A (0.66) MGLLKMT2APOLBRAB9AALDH1A1
SCHEMBL14581343 0.68 MAPK1 (0.39) MAPK1HSP90AA1PKMNPSR1MGLL
SCHEMBL13057567 0.68 ALDH1A1 (0.51) MAPK1HSP90AA1PKMNPSR1MGLL
SCHEMBL13296173 0.67 FAAH (0.54) MAPK1HSP90AA1NPSR1MGLLKMT2A
SCHEMBL13296199 0.67 MGLL (0.54) NPSR1MGLLKMT2ARAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003729-B2 comprising crosslinkable polyvinylalcohol, polyvinylphenol, polyhydroxyphenylmaleimide, aromatic polyimides and crosslinking agent; resist to heat and chemical; organic thin film transistor SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-08-23 US disclosed