Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.74 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12372035 | 0.85 | CTSL (1.00) | CTSLCTSKCTSS | |
| SCHEMBL12371600 | 0.85 | CTSL (1.00) | CTSLCTSKCTSS | |
| SCHEMBL2374682 | 0.78 | SCN9A (0.61) | CTSLSCN9ACTSKCTSSCTSB | |
| SCHEMBL2374657 | 0.78 | SCN9A (0.61) | CTSLSCN9ACTSKCTSSCTSB | |
| SCHEMBL12371614 | 0.78 | CTSL (0.67) | CTSLSCN9ACTSKCTSBALDH1A1 | |
| SCHEMBL4216378 | 0.77 | CTSK (0.65) | CTSLCTSKCTSSCTSBACE | |
| SCHEMBL4224863 | 0.77 | CTSK (0.65) | CTSLCTSKCTSSCTSBACE | |
| SCHEMBL12372025 | 0.76 | CTSL (0.71) | CTSLSCN9ACTSKCTSBGRM7 | |
| SCHEMBL12371604 | 0.75 | CTSS (0.60) | CTSLCTSKCTSSCTSBACE | |
| SCHEMBL23833928 | 0.75 | CTSK (0.51) | CTSLSCN9ACTSKCTSBGRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207726-A1 | Inhibitors of Human Cathepsin L, Cathepsin B, and Cathepsin S | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207726-A1 | Inhibitors of Human Cathepsin L, Cathepsin B, and Cathepsin S | CTSB, CTSS, CTSV | CTSL 7/4885SCN9A 3777/4885CTSK 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.