SCHEMBL12373559

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10201495	0.88	PTGES (0.40)	ALDH1A1TSHRLMNAPTGESPRCP
	SCHEMBL12373556	0.84	UCHL1 (0.43)	UCHL1GABRG2GABRB3GABRA5GABRA4
	SCHEMBL19488774	0.83	GABRG2 (0.33)	GABRG2GABRB3GABRA5GABRA4
	SCHEMBL12373564	0.83	GABRG2 (0.33)	GABRG2GABRB3GABRA5GABRA4
	SCHEMBL10201124	0.83	HCRTR1 (0.41)	UCHL1ALDH1A1TSHRLMNAPTGES
	SCHEMBL10121466	0.83	PRCP (0.38)	UCHL1TSHRLMNAPTGESPRCP
	SCHEMBL203367	0.82	HCRTR1 (0.46)	UCHL1GABRG2GABRB3GABRA5GABRA4
	SCHEMBL2708720	0.82	HCRTR1 (0.46)	UCHL1GABRG2GABRB3GABRA5GABRA4
	SCHEMBL19488784	0.82	UCHL1 (0.41)	UCHL1ALDH1A1GABRG2GABRB3GABRA5
	SCHEMBL18782896	0.77	PRCP (0.34)	TSHRLMNAPTGESPRCPHCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.