Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 4/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12373564 | 1.00 | GABRG2 (0.33) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL12373586 | 0.89 | GPR119 (0.33) | GPR119 | |
| SCHEMBL19488777 | 0.89 | GPR119 (0.33) | GPR119 | |
| SCHEMBL10201500 | 0.89 | GPR119 (0.33) | GPR119 | |
| SCHEMBL10201125 | 0.84 | USP30 (0.34) | — | |
| SCHEMBL12373506 | 0.84 | USP30 (0.34) | — | |
| SCHEMBL12373562 | 0.84 | GABRA1 (0.42) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL19488770 | 0.84 | GABRA1 (0.42) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL12373559 | 0.83 | UCHL1 (0.41) | GABRG2GABRB3GABRA5GABRA4 | |
| SCHEMBL12295800 | 0.82 | GABRA5 (0.38) | GABRG2GABRB3GABRA5GABRA1GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |