Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 10/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18483661 | 0.88 | ADK (0.54) | ADKSLC29A1ADORA3ADORA1ADORA2A | |
| SCHEMBL17800857 | 0.83 | ADK (0.71) | ADKSLC29A1ALDH1A1TP53HTT | |
| SCHEMBL10292987 | 0.81 | TK1 (0.47) | ADKLMNATP53DNMT1HTT | |
| SCHEMBL1738436 | 0.81 | CYP2C19 (0.41) | ADKSLC29A1CYP2C19ADORA3ADORA1 | |
| SCHEMBL6732905 | 0.81 | CYP2C19 (0.41) | ADKSLC29A1CYP2C19ADORA3ADORA1 | |
| SCHEMBL18483514 | 0.79 | ADK (0.58) | ADKSLC29A1GMNNALDH1A1LMNA | |
| Nelarabine SCHEMBL2143756 | 0.78 | CYP2C19 (0.71) | SLC29A1CYP2C19ADORA3ADORA1ADORA2A | |
| Nelarabine SCHEMBL13575801 | 0.78 | CYP2C19 (0.71) | SLC29A1CYP2C19ADORA3ADORA1ADORA2A | |
| Nelarabine SCHEMBL20769831 | 0.78 | CYP2C19 (0.71) | SLC29A1CYP2C19ADORA3ADORA1ADORA2A | |
| Nelarabine SCHEMBL18321891 | 0.78 | CYP2C19 (0.71) | SLC29A1CYP2C19ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003769-B2 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-8003769-B2 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-20100292457-A1 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292457-A1 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2010-11-18 | — | — | US | disclosed |
| US-7678892-B2 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2010-03-16 | — | — | US | disclosed |
| US-7678892-B2 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2010-03-16 | — | — | US | disclosed |
| US-20070293662-A1 | Dye-labeled ribonucleotide triphosphates | APPLERA CORPORATION (US) | 2007-12-20 | — | — | US | disclosed |
| US-20070293662-A1 | Dye-labeled ribonucleotide triphosphates | APPLERA CORPORATION (US) | 2007-12-20 | — | — | US | disclosed |
| US-7262029-B2 | Dye-labeled ribonucleotide triphosphates | APPLERA CORPORATION (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262029-B2 | Dye-labeled ribonucleotide triphosphates | APPLERA CORPORATION (US) | 2007-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292457-A1 | Dye-labeled ribonucleotide triphosphates | DUT, POLRMT, SAMHD1 | ADK 327/4885SLC29A1 101/4885CYP2C19 3643/4885 |
| US-20070293662-A1 | Dye-labeled ribonucleotide triphosphates | DUT, POLRMT, SAMHD1 | ADK 327/4885SLC29A1 101/4885CYP2C19 3643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.