SCHEMBL123770

SCHEMBL123770

CCCCCCCCCCCCCCCCCC(=O)NC1COCCN1CCC

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 6/20 0.46
CNR1 P21554 5/20 0.46
CNR2 P34972 4/20 0.46
GNAI3 P08754 1/20 0.42
GNAO1 P09471 1/20 0.42
GNAI1 P63096 1/20 0.42
NAAA Q02083 3/20 0.41
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL9844375 0.96 TRPV1 (0.43) TRPV1CNR1CNR2GNAI3GNAO1
Phosphoric Acid SCHEMBL9844239 0.95 TRPV1 (0.42) TRPV1CNR1CNR2GNAI3GNAO1
Lactic Acid SCHEMBL9843961 0.92 MEN1 (0.40) TRPV1CNR1CNR2ALDH1A1LMNA
SCHEMBL122497 0.89 TRPV1 (0.35) TRPV1CNR1CNR2GNAI3GNAO1
Citric Acid SCHEMBL9844145 0.88 OPRD1 (0.37) TRPV1CNR1CNR2GNAI3GNAO1
Acetic Acid SCHEMBL9844165 0.86 TRPV1 (0.33) TRPV1CNR1CNR2ALDH1A1LMNA
Phosphoric Acid SCHEMBL9844199 0.85 ALDH1A1 (0.33) TRPV1CNR1CNR2ALDH1A1LMNA
Lactic Acid SCHEMBL6445485 0.84 FAAH (0.36) TRPV1CNR1CNR2ALDH1A1LMNA
Citric Acid SCHEMBL9844312 0.79 ALDH1A1 (0.34) ALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL176250 0.75 MEN1 (0.41) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393469-B1 Process of treating hair RHODIA OPERATIONS (FR) 2016-10-12 EP claimed
US-20100278906-A1 MOISTURIZING ANTIMICROBIAL COMPOSITION GOLD BOND CO LLC 2010-11-04 US claimed
WO-1999053890-A1 CONDITIONING SHAMPOO AMWAY CORPORATION (US) 1999-10-28 WO claimed
US-5945093-A CONSISTS OF ANIONIC AND CATIONIC SURFACTANTS, AN ACID NEUTRALIZED AMIDONAMINE, WATER INSOLUBLE POLYSILOXANE AS CONDITIONING AGENT, DECADIENE CROSSLINKED MALEIC ANHDRIDE-METHYL VINYL ETHER COPOLYMER, FREE OF POLYHYDRIC COMPOUND AMWAY CORPORATION (US) 1999-08-31 US claimed
EP-0617953-B1 Clear conditioning composition CURTIS HELENE IND INC (US) 1998-11-18 EP claimed
US-5556615-A Clear conditioning composition HELENE CURTIS, INC. (US) 1996-09-17 US claimed
EP-0617953-A1 Clear conditioning composition Helene Curtis Industries, Inc. (US) 1994-10-05 EP claimed
US-5328685-A Amidoamine salt, silicone compound containing quaternary ammonium group HELENE CURTIS, INC. (US) 1994-07-12 US claimed
EP-0465734-B1 Clear conditioning composition and method to impart improved properties to the hair CURTIS HELENE IND INC (US) 1994-03-02 EP claimed
US-5198209-A Surfactants AMWAY CORPORATION (US) 1993-03-30 US claimed
EP-0465734-A1 Clear conditioning composition and method to impart improved properties to the hair HELENE CURTIS, INC. (US) 1992-01-15 EP claimed
EP-0410659-A2 Method and composition to impart improved conditioning properties to the hair HELENE CURTIS, INC. (US) 1991-01-30 EP claimed
US-4976956-A Water soluble and oil soluble quaternary ammonium compounds and amidoamine HELENE CURTIS, INC. (US) 1990-12-11 US claimed
US-4954335-A QUATERNARY AMMONIUM COMPOUND, AMIDOAMINE, POLYSILOXANE, NONIONIC SURFACTANT, ALCOHOL HELENE CURTIS, INC. (US) 1990-09-04 US claimed
US-8388991-B2 Moisturizing antimicrobial composition CHATTEM, INC. (US) 2013-03-05 US disclosed
EP-2424354-A2 MOISTURIZING ANTIMICROBIAL COMPOSITION Signal Investment & Management Co. (US) 2012-03-07 EP disclosed
WO-2010127231-A2 MOISTURIZING ANTIMICROBIAL COMPOSITION SIGNAL INVESTMENT AND MANAGEMENT CO. (US) 2010-11-04 WO disclosed
EP-0410659-A2 Method and composition to impart improved conditioning properties to the hair HELENE CURTIS, INC. (US) 1991-01-30 EP disclosed
US-4976956-A Water soluble and oil soluble quaternary ammonium compounds and amidoamine HELENE CURTIS, INC. (US) 1990-12-11 US disclosed
US-4954335-A QUATERNARY AMMONIUM COMPOUND, AMIDOAMINE, POLYSILOXANE, NONIONIC SURFACTANT, ALCOHOL HELENE CURTIS, INC. (US) 1990-09-04 US disclosed