Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122497 | 0.94 | TRPV1 (0.35) | MEN1KMT2ATP53CYP3A4CYP2D6 | |
| Acetic Acid SCHEMBL9844165 | 0.94 | TRPV1 (0.33) | FAAHMEN1KMT2ATP53CYP3A4 | |
| Lactic Acid SCHEMBL9843961 | 0.92 | MEN1 (0.40) | FAAHMEN1KMT2ATP53CYP3A4 | |
| Phosphoric Acid SCHEMBL9844199 | 0.90 | ALDH1A1 (0.33) | MEN1KMT2ATP53CYP3A4CYP2D6 | |
| Citric Acid SCHEMBL9844312 | 0.86 | ALDH1A1 (0.34) | MAPTLMNASMN1; SMN2PLA2G10ALDH1A1 | |
| SCHEMBL123770 | 0.84 | TRPV1 (0.46) | LMNASMN1; SMN2ALDH1A1HTTTRPV1 | |
| Acetic Acid SCHEMBL9844375 | 0.83 | TRPV1 (0.43) | MEN1KMT2ATP53CYP3A4CYP2D6 | |
| Phosphoric Acid SCHEMBL9844239 | 0.80 | TRPV1 (0.42) | LMNASMN1; SMN2ALDH1A1HTTTRPV1 | |
| Citric Acid SCHEMBL9844145 | 0.76 | OPRD1 (0.37) | MEN1KMT2ATP53CYP3A4CYP2D6 | |
| Lactic Acid SCHEMBL29975332 | 0.73 | GNAI3 (0.41) | FAAHMEN1KMT2ATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410659-A2 | Method and composition to impart improved conditioning properties to the hair | HELENE CURTIS, INC. (US) | 1991-01-30 | — | — | EP | claimed |
| US-4976956-A | Water soluble and oil soluble quaternary ammonium compounds and amidoamine | HELENE CURTIS, INC. (US) | 1990-12-11 | — | — | US | claimed |
| US-4168302-A | SUCH AS STEARYLAMIDOPROPYLMORPHOLINE LACTATE | THE RICHARDSON COMPANY (US) | 1979-09-18 | — | — | US | claimed |
| EP-3843694-B1 | EMULSION-BASED PERSONAL CARE COMPOSITIONS AND METHODS FOR THE SAME | COLGATE PALMOLIVE CO (US) | 2026-01-21 | — | — | EP | disclosed |
| US-20250195341-A1 | Personal Care Compositions Incorporating Natural Benefit Agents And Methods For The Same | COLGATE-PALMOLIVE COMPANY (US) | 2025-06-19 | — | — | US | disclosed |
| US-12329845-B2 | Emulsion-based personal care compositions and methods for the same | COLGATE-PALMOLIVE COMPANY (US) | 2025-06-17 | — | — | US | disclosed |
| EP-3836889-B1 | SOLID CLEANSING COMPOSTIONS AND METHODS FOR THE SAME | COLGATE PALMOLIVE CO (US) | 2025-05-14 | — | — | EP | disclosed |
| EP-3490682-B1 | LIQUID CLEANSING COMPOSITIONS WITH AN ANTIBACTERIAL SYSTEM AND METHOD OF MANUFACTURING THEREOF | COLGATE PALMOLIVE CO (US) | 2025-03-05 | — | — | EP | disclosed |
| US-20240293302-A1 | Solid Personal Care Compositions and Methods for Preventing and Treating Pollution Damage to Skin | COLGATE-PALMOLIVE COMPANY (US) | 2024-09-05 | — | — | US | disclosed |
| US-12070515-B2 | Silicone free emulsion-based personal care compositions and methods for the same | COLGATE-PALMOLIVE COMPANY (US) | 2024-08-27 | — | — | US | disclosed |
| US-20240269052-A1 | Sulfate-Free Personal Care Compositions and Methods for Preventing and Treating Pollution Damage to Skin | COLGATE-PALMOLIVE COMPANY (US) | 2024-08-15 | — | — | US | disclosed |
| EP-0313561-B1 | COMPOSITIONS USED IN PERMANENT STRUCTURE ALTERING OF HAIR | ISP INVESTMENTS INC. (US) | 1992-12-02 | — | — | EP | disclosed |
| EP-0287649-A4 | COMPOSITIONS USED IN PERMANENT STRUCTURE ALTERING OF HAIR | — | 1991-08-21 | — | — | EP | disclosed |
| US-4976956-A | Water soluble and oil soluble quaternary ammonium compounds and amidoamine | HELENE CURTIS, INC. (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0313561-A4 | COMPOSITIONS USED IN PERMANENT STRUCTURE ALTERING OF HAIR. | GAF CORP (US) | 1989-10-12 | — | — | EP | disclosed |
| EP-0313561-A1 | COMPOSITIONS USED IN PERMANENT STRUCTURE ALTERING OF HAIR. | GAF CORP (US) | 1989-05-03 | — | — | EP | disclosed |
| EP-0287649-A1 | COMPOSITIONS USED IN PERMANENT STRUCTURE ALTERING OF HAIR | GAF CHEMICALS CORPORATION (US) | 1988-10-26 | — | — | EP | disclosed |
| WO-1988002997-A1 | COMPOSITIONS USED IN PERMANENT STRUCTURE ALTERING OF HAIR | GAF CORPORATION (US) | 1988-05-05 | — | — | WO | disclosed |
| WO-1988000186-A1 | COMPOSITIONS USED IN PERMANENT STRUCTURE ALTERING OF HAIR | GAF CORPORATION (US) | 1988-01-14 | — | — | WO | disclosed |
| US-4168302-A | SUCH AS STEARYLAMIDOPROPYLMORPHOLINE LACTATE | THE RICHARDSON COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12070515-B2 | Silicone free emulsion-based personal care compositions and methods for the same | CUTA, LAGE3, GLUL | FAAH 2192/4885MEN1 1288/4885KMT2A 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.