Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 11/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.37 |
| ▸ | GABRP | O00591 | 7/20 | 0.37 |
| ▸ | GABRD | O14764 | 7/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.37 |
| ▸ | GABRE | P78334 | 7/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377307 | 0.83 | PDE2A (0.38) | GABRB3GABRA2GABRB2GLP1RPDE2A | |
| SCHEMBL12377328 | 0.83 | GLP1R (0.36) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL12377296 | 0.77 | EGFR (0.48) | PDE2AP2RX3 | |
| SCHEMBL12377281 | 0.76 | P2RX3 (0.44) | P2RX3 | |
| SCHEMBL12377318 | 0.75 | CACNA1D (0.50) | CYP2D6CYP2C19CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL12377291 | 0.73 | MET (0.43) | — | |
| SCHEMBL12377298 | 0.73 | GABRA2 (0.39) | GABRB3GABRA2GABRB2 | |
| SCHEMBL12377322 | 0.73 | KMT2A (0.44) | KCNH2P2RX3 | |
| SCHEMBL11520254 | 0.72 | CSNK1E (0.38) | CASR | |
| SCHEMBL12377297 | 0.72 | HSD17B10 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989422-B2 | Antibacterial agents | ALCHEMIA LIMITED (AU) | 2011-08-02 | — | — | US | disclosed |
| US-7989422-B2 | Antibacterial agents | ALCHEMIA LIMITED (AU) | 2011-08-02 | — | — | US | disclosed |
| US-20090023669-A1 | Antibacterial Agents | ALCHEMIA LIMITED (AU) | 2009-01-22 | — | — | US | disclosed |
| US-20090023669-A1 | Antibacterial Agents | ALCHEMIA LIMITED (AU) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023669-A1 | Antibacterial Agents | MRPL21, FUT6, FUT5 | CYP2D6 3365/4885CYP2C19 3858/4885CYP2C9 4203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.