Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.35 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377321 | 0.83 | CYP2D6 (0.39) | GLP1RPDE2AGABRB3GABRA2GABRB2 | |
| SCHEMBL12377307 | 0.83 | PDE2A (0.38) | GLP1RPDE2AGABRB3GABRA2GABRB2 | |
| SCHEMBL12377296 | 0.77 | EGFR (0.48) | PDE2AP2RX3 | |
| SCHEMBL12377281 | 0.76 | P2RX3 (0.44) | P2RX3SMN1; SMN2 | |
| SCHEMBL8044540 | 0.74 | ALDH1A1 (0.47) | PDE2A | |
| SCHEMBL12377322 | 0.73 | KMT2A (0.44) | P2RX3SMN1; SMN2 | |
| SCHEMBL12377298 | 0.73 | GABRA2 (0.39) | GABRB3GABRA2GABRB2 | |
| SCHEMBL12377291 | 0.73 | MET (0.43) | SMN1; SMN2 | |
| SCHEMBL12377297 | 0.72 | HSD17B10 (0.43) | GABRB3GABRA2GABRB2P2RX3SMN1; SMN2 | |
| SCHEMBL12377280 | 0.71 | GAA (0.39) | PDE2AP2RX3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989422-B2 | Antibacterial agents | ALCHEMIA LIMITED (AU) | 2011-08-02 | — | — | US | disclosed |
| US-20090023669-A1 | Antibacterial Agents | ALCHEMIA LIMITED (AU) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023669-A1 | Antibacterial Agents | MRPL21, FUT6, FUT5 | GLP1R 927/4885PDE2A 2984/4885GABRB3 4206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.