SCHEMBL12379904

SCHEMBL12379904

Cc1cccc(C)c1/N=C\c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
LMNA P02545 2/20 0.46
G6PD P11413 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
LIG1 P18858 2/20 0.41
KDM4E B2RXH2 4/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
GAA P10253 3/20 0.40
ALDH1A1 P00352 3/20 0.40
GLA P06280 2/20 0.40
LIG3 P49916 1/20 0.40
LIG4 P49917 1/20 0.40
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
CA12 O43570 1/20 0.38
PTGS2 P35354 1/20 0.38
CA9 Q16790 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18489660 1.00 L3MBTL1 (0.46) L3MBTL1LMNAG6PDMEN1KMT2A
SCHEMBL18489661 1.00 L3MBTL1 (0.46) L3MBTL1LMNAG6PDMEN1KMT2A
SCHEMBL11048071 0.83 ALDH1A1 (0.46) L3MBTL1LMNAG6PDMEN1KMT2A
SCHEMBL5837575 0.83 ALDH1A1 (0.46) L3MBTL1LMNAG6PDMEN1KMT2A
SCHEMBL27890108 0.82 MYC (0.51) L3MBTL1LMNAMEN1KMT2ALIG1
SCHEMBL11390813 0.82 GAA (0.48) LMNAMEN1KMT2AKDM4ECA1
SCHEMBL11275875 0.82 LMNA (0.41) L3MBTL1LMNAG6PDMEN1KMT2A
SCHEMBL11275872 0.82 LMNA (0.41) L3MBTL1LMNAG6PDMEN1KMT2A
SCHEMBL11271321 0.79 ALDH1A1 (0.59) L3MBTL1G6PDMEN1KMT2AKDM4E
SCHEMBL5074324 0.78 CYP2C9 (0.52) L3MBTL1LMNAMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3184171-B1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-03-20 EP disclosed
US-7998895-B2 Catalysts for olefin polymerization E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-08-16 US disclosed
US-7998895-B2 Catalysts for olefin polymerization E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-08-16 US disclosed
US-20100222531-A1 CATALYSTS FOR OLEFIN POLYMERIZATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-02 US disclosed
US-20100222531-A1 CATALYSTS FOR OLEFIN POLYMERIZATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-02 US disclosed
US-20100029469-A1 CATALYSTS FOR OLEFIN POLYMERIZATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US disclosed
US-20100029469-A1 CATALYSTS FOR OLEFIN POLYMERIZATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US disclosed
US-7439314-B2 Catalysts for olefin polymerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-10-21 US disclosed
US-7439314-B2 Catalysts for olefin polymerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100222531-A1 CATALYSTS FOR OLEFIN POLYMERIZATION PORCN, PUF60, CAD L3MBTL1 2478/4885LMNA 2657/4885G6PD 4196/4885
US-20100029469-A1 CATALYSTS FOR OLEFIN POLYMERIZATION PORCN, PUF60, CAD L3MBTL1 2478/4885LMNA 2657/4885G6PD 4196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.