Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | LIG1 | P18858 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048071 | 1.00 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1LMNALIG1CA1 | |
| SCHEMBL12379904 | 0.83 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1LMNALIG1CA1 | |
| SCHEMBL18489660 | 0.83 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1LMNALIG1CA1 | |
| SCHEMBL18489661 | 0.83 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1LMNALIG1CA1 | |
| SCHEMBL11415401 | 0.79 | CA2 (0.57) | ALDH1A1CA1CA2KDM4EGLA | |
| SCHEMBL11275875 | 0.78 | LMNA (0.41) | ALDH1A1L3MBTL1LMNALIG1CA1 | |
| SCHEMBL11275872 | 0.78 | LMNA (0.41) | ALDH1A1L3MBTL1LMNALIG1CA1 | |
| SCHEMBL14337301 | 0.77 | KDM4E (0.52) | ALDH1A1L3MBTL1LMNALIG1CA1 | |
| SCHEMBL14821445 | 0.76 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1LMNACA1CA2 | |
| SCHEMBL445024 | 0.75 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060768-B2 | Polymerization of olefinic compounds | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-06-13 | — | — | US | disclosed |
| US-20040158012-A1 | Polymerization of olefinic compounds | BROOKHART MAURICE S (US) | 2004-08-12 | — | — | US | disclosed |
| US-6710007-B2 | TRANSITION METAL COMPLEXES OF IMINES, AMINES OR PHOSPHINES CONTAINING ESTERS OR AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-03-23 | — | — | US | disclosed |
| EP-1355956-A2 | POLYMERIZATION OF OLEFINIC COMPOUNDS | E.I. Dupont de Nemours and Company (US) | 2003-10-29 | — | — | EP | disclosed |
| US-20030125485-A1 | Polymerization of olefinic compounds | NORTH CAROLINA AT CHAPEL HILL, UNIVERSITY OF | 2003-07-03 | — | — | US | disclosed |
| WO-2002059165-A2 | POLYMERIZATION OF OLEFINIC COMPOUNDS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |
| US-4473579-A | REDUCING CHOLESTEROL ESTER CONTENT IN ARTERIES | AMERICAN CYANAMID COMPANY (US) | 1984-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125485-A1 | Polymerization of olefinic compounds | PORCN, PHOSPHO1, TEC | ALDH1A1 2253/4885L3MBTL1 3233/4885LMNA 3756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.