Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.69 |
| ▸ | DRD4 | P21917 | 6/20 | 0.69 |
| ▸ | DRD3 | P35462 | 6/20 | 0.69 |
| ▸ | GAA | P10253 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | GOT1 | P17174 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161609 | 0.82 | DRD4 (1.00) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL2161659 | 0.78 | DRD2 (0.73) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL2161800 | 0.78 | DRD2 (0.59) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL7940933 | 0.77 | DRD2 (0.55) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL2161629 | 0.76 | DRD2 (0.70) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL13493196 | 0.76 | DRD2 (0.70) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL2161656 | 0.76 | DRD2 (0.73) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL7732059 | 0.76 | DRD2 (0.69) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL6068278 | 0.75 | DRD2 (0.50) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL27542561 | 0.75 | DRD2 (0.50) | DRD2DRD4DRD3GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183991-A1 | 5HT7 RECEPTOR LIGANDS AND COMPOSITIONS COMPRISING THE SAME | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183991-A1 | 5HT7 RECEPTOR LIGANDS AND COMPOSITIONS COMPRISING THE SAME | HTR7, HTR1A, HTR6 | DRD2 43/4885DRD4 70/4885DRD3 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.