Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.55 |
| ▸ | DRD4 | P21917 | 6/20 | 0.55 |
| ▸ | DRD3 | P35462 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 7/20 | 0.39 |
| ▸ | HTR6 | P50406 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 4/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | GOT1 | P17174 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939820 | 0.86 | DRD2 (0.57) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL7939784 | 0.83 | ALDH1A1 (0.47) | DRD2DRD4DRD3MAPT | |
| SCHEMBL7942668 | 0.81 | SLC6A2 (0.51) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL7939838 | 0.80 | DRD2 (0.60) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL12401748 | 0.77 | DRD2 (0.69) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL8053407 | 0.75 | MEN1 (0.47) | DRD2GAAMEN1KMT2AHTR1A | |
| Hydrochloric Acid SCHEMBL8143284 | 0.74 | MEN1 (0.46) | DRD2GAAMEN1KMT2AHTR1A | |
| SCHEMBL2161609 | 0.73 | DRD4 (1.00) | DRD2DRD4DRD3GAAMAPT | |
| SCHEMBL7944691 | 0.70 | RAB9A (0.44) | MEN1KMT2A | |
| SCHEMBL7939807 | 0.67 | HTR1A (0.56) | DRD2DRD4DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242448-B1 | Trisubstituted-oxazole derivatives as serotonin ligands | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | claimed |
| US-6242448-B1 | Trisubstituted-oxazole derivatives as serotonin ligands | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | disclosed |